Reed-Sternberg cells
Citation, DOI, disclosures and article data
Citation:
Knipe H, Glick Y, Weerakkody Y, Reed-Sternberg cells. Reference article, Radiopaedia.org (Accessed on 06 Dec 2024) https://doi.org/10.53347/rID-40776
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rID:
40776
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Disclosures:
At the time the article was created Henry Knipe had no recorded disclosures.
View Henry Knipe's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Yaïr Glick had no recorded disclosures.
View Yaïr Glick's current disclosures
Revisions:
3 times, by
3 contributors -
see full revision history and disclosures
Systems:
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Synonyms:
- Lacuna cells
- Reed-Sternberg cell
- Lacuna cell
Reed-Sternberg cells are a classical finding diagnostic of Hodgkin lymphoma. They are giant, multinucleated cells with abundant pale cytoplasm. Reed-Sternberg cells are rare, making up <1% of lymphoid tissue, with the background consisting of lymphocytes, plasma cells, eosinophils and macrophages.
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References
- 1. Koss' diagnostic cytology and its histopathologic bases. LWW. ISBN:0781719283. Read it at Google Books - Find it at Amazon
- 2. Wahl CE. The Hardcore Pathology:. Lippincott Williams & Wilkins. ISBN:1405104988. Read it at Google Books - Find it at Amazon
- 3. Küppers R, Klein U, Schwering I et-al. Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling. J. Clin. Invest. 2003;111 (4): 529-37. doi:10.1172/JCI16624 - Free text at pubmed - Pubmed citation
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