Renal osteodystrophy

Dr Henry Knipe and A.Prof Frank Gaillard et al.

Renal osteodystrophy (ROD), also known as uraemic osteopathy, is the constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure, due to concurrent and superimposed:

  • osteomalacia (adults) / rickets (children)
  • secondary hyperparathyroidism: abnormal calcium and phosphate metabolism
    • bone resorption
    • osteosclerosis
    • soft tissue and vascular calcifications
    • brown tumours
  • aluminum intoxication, e.g. if the patient is on dialysis

Radiographic features

Imaging findings are many and varied:

Differential diagnosis

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Article information

rID: 3935
Synonyms or Alternate Spellings:
  • ROD
  • Renal osteodystrophy (ROD)
  • Uraemic osteopathy
  • Uremic osteopathy

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Cases and figures

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    Case 1: subperiosteal resorption
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    Case 2: Rugger Jersey Spine
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    Case 3: Brown tumours
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    Case 5
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    Brown Tumors
    Case 6 : Brown tumours
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    Case 7
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    Renal osteodystro...
    Case 8
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    CXR : cropped to ...
    Case 9: soft tissue and ligament calcification
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    Case 10: amyloid arthropathy
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    Case 11: osteosclerosis and multiple lytic lesions of bone resorption
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    Case 12: salt and pepper skull
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    Case 13: salt and pepper skull
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    Case 14
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