Restrictive lung disease
Citation, DOI & article data
Restrictive lung disease (or a restrictive ventilatory defect) is a physiological spirometric term given to a heterogeneous group of conditions that result in restricted lung expansion. It is not equal to but can be related to pulmonary fibrosis as extrapulmonary e.g. thoracic wall conditions can result in a restrictive lung disease pattern.
Its etiology can be highly variable ranging from:
- intrinsic - with lung parenchymal involvement: interstitial lung diseases or
- extrinsic to the lung -
Patients with a restrictive lung disease pattern can often have decreased lung volumes, increased work of breathing, and inadequate ventilation and/or oxygenation. Pulmonary function tests often demonstrate a decrease in the forced vital capacity (FVC).
- 1. Hansell DM. Classification of diffuse lung diseases: why and how. (2013) Radiology. 268 (3): 628-40. doi:10.1148/radiol.13120908 - Pubmed
- 2. Won CH, Kryger M. Sleep in patients with restrictive lung disease. (2014) Clinics in chest medicine. 35 (3): 505-12. doi:10.1016/j.ccm.2014.06.006 - Pubmed
- 3. Robinson HC. Respiratory Conditions Update: Restrictive Lung Disease. (2016) FP essentials. 448: 29-34. Pubmed
- 4. Johari J, Sharifudin MA, Ab Rahman A, Omar AS, Abdullah AT, Nor S, Lam WC, Yusof MI. Relationship between pulmonary function and degree of spinal deformity, location of apical vertebrae and age among adolescent idiopathic scoliosis patients. (2016) Singapore medical journal. 57 (1): 33-8. doi:10.11622/smedj.2016009 - Pubmed
- 5. Dixon AE, Peters U. The effect of obesity on lung function. (2018) Expert review of respiratory medicine. 12 (9): 755-767. doi:10.1080/17476348.2018.1506331 - Pubmed