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Reverse rim sign (kidney)

Last revised by Joshua Yap on 11 May 2023

The reverse rim sign describes relative hypoenhancement of the renal cortex and normal enhancement of the renal medulla on contrast-enhanced CT and MRI. This enhancement pattern can also be visualized using contrast-enhanced ultrasound 2.

It is a typical finding of renal cortical necrosis that may occur in the setting of renal transplant rejection, intravascular hemolysis, shock, and as an obstetric complication 3.

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Cases and figures

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