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Reverse target sign (cirrhotic nodules)

Last revised by Brian Robichaud on 03 Dec 2021

A reverse target sign is a potential ultrasound marker for cirrhotic nodules on ultrasound. It represents central iso-hyperechogenicity with surrounding hyperechoic rim. This sign is useful to differentiate metastases from cirrhotic nodules, conversely the target sign is seen with liver metastases.

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