Ritalin lung
Updates to Article Attributes
Body
was changed:
Ritalin lung describes pulmonary changes induced by IV exposure to methylphenidate (Ritalin).
Epidemiology
Methylphenidate is prescribed primarily for attention deficit hyperactivity disorder (ADHD) and narcolepsy, the latter being the only licensed indication in adults. It is in the piperidine class and is a structural analogue of amphetamine. It is used globally and marketed under several different brands, a well-known one being Ritalin. Off-label use forms an increasingly large proportion of prescriptions 5.
Radiographic features
HRCT chest
It classically givespan-lobular emphysematous change 1,4.
Differential diagnosis
General imaging differential considerations include:
- alpha 1 antitrypsin deficiency: lung changes can be almost indistinguishable on imaging1
- vanishing lung syndrome: tends to have more giant bullous spaces with para-septal empysema 3
-<p><strong>Ritalin lung</strong> describes pulmonary changes induced by IV exposure to methylphenidate (Ritalin).</p><h4>Radiographic features</h4><h5>HRCT chest</h5><p>It classically gives <a href="/articles/pan-lobular-emphysematous-change">pan-lobular emphysematous change</a> <sup>1,4</sup>.</p><h4>Differential diagnosis</h4><p>General imaging differential considerations include:</p><ul>- +<p><strong>Ritalin lung</strong> describes pulmonary changes induced by IV exposure to methylphenidate (Ritalin).</p><h4>Epidemiology</h4><p>Methylphenidate <span style="font-size:13px">is prescribed primarily for attention deficit hyperactivity disorder (ADHD) and narcolepsy, the latter being the only licensed indication in adults. It is in the piperidine class and is a structural analogue of amphetamine. It is used globally and marketed under several different brands, a well-known one being Ritalin. Off-label use forms an increasingly large proportion of prescriptions <sup>5</sup>.</span></p><h4>Radiographic features</h4><h5>HRCT chest</h5><p>It classically gives <a href="/articles/pan-lobular-emphysematous-change">pan-lobular emphysematous change</a> <sup>1,4</sup>.</p><h4>Differential diagnosis</h4><p>General imaging differential considerations include:</p><ul>
-<a href="/articles/alpha-1-antitrypsin-deficiency-2">alpha 1 antitrypsin deficiency</a>: lung changes can be almost indistinguishable on imaging <sup>1</sup>- +<a href="/articles/alpha-1-antitrypsin-deficiency-3">alpha 1 antitrypsin deficiency</a>: lung changes can be almost indistinguishable on imaging <sup>1</sup>
References changed:
- 5. Trenque T, Herlem E, Abou Taam M, Drame M. Methylphenidate off-label use and safety. (2014) SpringerPlus. 3: 286. <a href="https://doi.org/10.1186/2193-1801-3-286">doi:10.1186/2193-1801-3-286</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/25279275">Pubmed</a> <span class="ref_v4"></span>
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