Robust rheumatoid arthritis refers to a rare variant of rheumatoid arthritis with marked subchondral cysts and preserved bone density 1,2.
This entity is very rare, but is thought to occur more-so in males, especially those who are involved in physical labor 2.
Location and distribution of disease are most predominantly in the wrist (distal raioulnar, radiocarpal joints) and hands (metacarpophalangeal and interphalangeal joints), but may also affect different locations, such as feet. Compared to rheumatoid arthritis, patients present with much more attenuated pain and stiffness, and may even be asymptomatic 2.
Etiology is unknown, but thought to be related to use of hands with manual labor.
General appearance is typical of rheumatoid arthritis:
- marginal erosions
- ulnar deviation of metacarpophalangeal joints
- synovial prolipheration
Notable differences between it and rheumatoid arthritis:
- large subchondral cyst formations disproportionate to erosive changes
- lack of osteopaenia
History and etymology
Also known as arthritis robust or rheumatoid robustus, this entity was first described by de Haas WH et al. in 1973 3.
- 1. Sweeney SE, Harris Jr ED, Firestein GS. Clinical features of rheumatoid arthritis. InKelley's Textbook of Rheumatology 2013 Jan 1 (pp. 1109-1136). WB Saunders.
- 2. Prasad K, Rath D, Kundu BK. Arthritis Robustus: review of a case of an "abnormal" rheumatoid. (2014) SpringerPlus. 3: 606. doi:10.1186/2193-1801-3-606 - Pubmed
- 3. de Haas WH, de Boer W, Griffioen F, Oosten-Elst P. Rheumatoid arthritis, typus robustus. (1973) Annals of the rheumatic diseases. 32 (1): 91-2. doi:10.1136/ard.32.1.91 - Pubmed
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