Salt and pepper sign (skull)

Salt and pepper sign or pepper pot skull refers to multiple tiny well-defined lucencies in the calvaria caused by resorption of trabecular bone in hyperparathyroidism. There is a loss of definition between the inner and outer tables of the skull and a ground-glass appearance as well as spotty deossification.

Occasionally, the term is used synonymously (although inaccurately) with the raindrop skull appearance of multiple lytic lesions of multiple myeloma 4.

See also

Inspired signs
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Article information

rID: 21561
Section: Signs
Synonyms or Alternate Spellings:
  • Pepperpot skull
  • Salt and pepper skull
  • Salt and pepper appearance
  • Salt and pepper calvaria
  • Salt and pepper sign of the skull
  • Salt and pepper sign of the calvaria
  • Pepper pot skull

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