Sandwich sign (Marchiafava-Bignami disease)

The sandwich sign of Marchiafava-Bignami disease has been described for the appearance of the central layers of the corpus callosum which are preferentially involved by this disease.

T2 and FLAIR hyperintensities are seen in the central region of body and splenium of corpus callosum with sparing of peripheral dorsal and ventral layers of the corpus callosum.

See also

Inspired signs

Article information

rID: 27572
Section: Signs
Synonyms or Alternate Spellings:
  • Sandwich sign in Marchiafava-Bignami disease
  • Sandwich sign of Marchiafava-Bignami disease

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