Sarcopenia can be defined as significant loss of muscle function as a result of decreased muscle bulk. The definition was originally restricted to elderly individuals only, however many use it for people of any age.
A direct evaluation of muscle mass on imaging can be performed. Conversely, a reduction in grip strength and low gait speed may be used as functional markers.
Specific criteria include 1:
- grip strength
- <26 kg for men
- <16 kg for women
- low lean body mass (appendicular lean mass modified for body mass index)
- <0.789 for men
- <0.512 for women
Dual energy x-ray absorptiometry (DEXA) is the gold-standard imaging modality in the evaluation of sarcopenia and has been used for the greatest number of trials 1.