Schmorl nodes, also referred as intravertebral disc herniations, refer to protrusions of the cartilage of the intervertebral disc through the vertebral body endplate and into the adjacent vertebra. The protrusions may contact the marrow of the vertebra, leading to inflammation.
Quiescent Schmorl nodes are extremely common found in around 75% of autopsies, at all ages, more frequently in males 9. They are usually asymptomatic, and their etiological significance for back pain is controversial.
Acute Schmorl nodes, in contrast, are uncommon and are associated with inflammation and symptoms 9.
It is believed that Schmorl nodes develop following back trauma, although this is incompletely understood. A more recent study suggests nucleus pulposus pressure on the weakest part of the end plate or vertebral development process during early life as possible explanation 7.
In the acute stage, Schmorl nodes can be difficult to diagnose on plain radiography or detect due to sclerosis around the margin of the herniation not having had time to develop.
Usually, they are small nodular lucent lesions involving the inferior endplate of lower thoracic and lumbar vertebral bodies. However, the involvement of both the inferior and the superior endplates is not uncommon. A sclerotic margin may be present.
Schmorl nodes are better identified on CT images, showing the same pattern observed on radiographs.
Schmorl nodes are best seen on the sagittal sequences and usually exhibit the same signal characteristics as the adjacent disc, with a thin rim of sclerosis at the margins.
Acute herniation can appear more aggressive with surrounding bone marrow oedema and peripheral enhancement 9. These acute features evolve gradually over months 9.
Acute Schmorl nodes have been reported to be FDG-PET avid 9.
History and etymology
It is named after Christian Georg Schmorl (1861-1932), a German pathologist who first described them in 1927 9.
For chronic Schmorl nodes there is little differential as they have characteristic appearances.
Acute herniation on the other hand needs to be distinguished from discitis osteomyelitis and malignancy 9.
- spinal anatomy
- congential abnormalities of the spine
- spinal infection / inflammation / degeneration
- intervertebral disc
- intervertebral disc disease nomenclature
- lumbar disc disease
- acute calcific discitis
- acute disseminated encephalomyelitis (ADEM)
- Charcot-Marie-Tooth disease
- HIV vacuolar myelopathy
- HTLV-1 associated myelopathy (tropical spastic paraparesis)
- multiple sclerosis
- neuromyelitis optica (NMO) - (Devic's disease)
- transverse myelitis
- SCA3 (Machado-Joseph disease)
- subacute combined degeneration of the cord
- subacute necrotizing myelopathy
- tabes dorsalis
- spinal ischaemia
- spinal trauma
- spinal tumours and cysts
- spinal vascular malformations
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- 8. Abu-Ghanem S, Ohana N, Abu-Ghanem Y et-al. Acute schmorl node in dorsal spine: an unusual cause of a sudden onset of severe back pain in a young female. Asian Spine J. 2013;7 (2): 131-5. doi:10.4184/asj.2013.7.2.131 - Free text at pubmed - Pubmed citation
- 9. Diehn FE, Maus TP, Morris JM et-al. Uncommon Manifestations of Intervertebral Disk Pathologic Conditions. Radiographics. 2016;36 (3): 801-23. doi:10.1148/rg.2016150223 - Pubmed citation