Scleritis refers to inflammation of the sclera. It has a wide range of causes.

It can affect age group but usually those between ages 30 and 50 years. There is a recognised increased female predilection (F:M of ~2:1).

Information on the pathogenesis of scleritis is limited due to a lack of published data. However a predominant role for T cells in the inflammatory process has been postulated 1.

Scleritis can be associated with several systemic infective as well as non-infective systemic conditions which include 1:

One classification system is the Watson and Hayreh system which divides scleritis into anterior and posterior forms based upon the anatomic distribution.

  • anterior scleritis
    • diffuse anterior scleritis
    • nodular anterior scleritis
    • necrotising anterior scleritis with inflammation
    • scleromalacia perforans (necrotising anterior scleritis without inflammation)
  • posterior scleritis

Ocular ultrasound may play a role in the diagnosis and management of posterior scleritis.

Share article

Article information

rID: 37414
Synonyms or Alternate Spellings:
  • Inflammation of the sclera
  • Scleral inflammatory disease

Support Radiopaedia and see fewer ads

Updating… Please wait.

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.