Sclerosing stromal tumour of the ovary

Radswiki et al.

Sclerosing stromal tumour (SST) of the ovary is a rare ovarian neoplasm. It is considered a subtype of ovarian sex cord / stromal tumour and is included in the fibroma-thecoma group of ovarian tumors 9.

It occurs predominantly in young women, peaks around 2nd to 3rd decades of life 1-2

Patients may have menstrual irregularity and/or pelvic pain 4. It is usually hormonally inactive, but it may occasionally have an oestrogenic effect (even more rarely an androgenic effect).

It is histologically characterized by cellular heterogeneity, prominent vasculature, and a pseudolobular appearance composed of cellular and hypocellular areas. They generally tend to be unilateral 3.

Ultrasound 

Described sonographic features (whilst being nonspecific) include tumour with multilocular cystic components and irregularly thickened septa and tumor walls or a solid tumor including several small cystic components 5

Pelvic MRI

Described signal characteristics include 5

  • T2
    • signal intensities of the cystic components are high and those of the solid components were inhomogeneous, ranging from intermediate-high to high
    • MR may show pseudolobulation 7-8 of the lesion which consists of low-intensity nodules set against high-intensity stroma on T2-weighted images 7
  • T1 C+ (Gd): dynamic imaging may show marked early enhancement of the solid components 5,7
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Article Information

rID: 15101
System: Gynaecology
Section: Pathology
Synonyms or Alternate Spellings:
  • Sclerosing stromal tumor of the ovary
  • SST ovary
  • Sclerosing stromal tumour of the ovary (SST)
  • Sclerosing stromal tumour (SST) of the ovary
  • Ovarian sclerosing stromal tumour

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Cases and Figures

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