Seckel syndrome

Seckel syndrome is an autosomal recessive congenital dwarfing disorder.

The estimated incidence is ~1:10,000. There is no recognized gender predilection.

It is clinically characterized by many features including:

It is considered a type of primordial dwarfism

The abnormal genes have been mapped to two loci on chromosomes 3q and 18p 7,8.

May show any of the clinical features above.
Additional skeletal features may include:

Named after Helmut Paul George Seckel (1900-1960) 9, a German-American pediatrician.

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Article information

rID: 12453
Section: Syndromes
Synonyms or Alternate Spellings:
  • Seckel's syndrome
  • Microcephalic primordial dwarfism
  • Bird-headed dwarfism
  • Virchow-Seckel dwarfism

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