Secondary organizing pneumonia

Secondary organizing pneumonia (SOP) refers to organizing pneumonia that can be attributed to a specific cause, in contrast to cryptogenic organizing pneumonia (COP).

Pathology

Etiology

SOP can be attributed to the following causes 1:

Prior infection
  • bacteria
    • atypical pneumonias (e.g. Legionella, Mycoplasma etc.)
    • Streptococcus pneumoniae
    • Staphylococcus aureus
    • Pseudomonas aeruginosa
  • fungi
    • Cryptococcus neoformans
    • Pneumocystis jiroveci
    • Penicillium janthinellum
  • viruses
    • adenovirus, herpes, CMV, influenza, HIV, RSV
  • parasites
    • Plasmodium vivax
    • Dirofilaria immitis
Drugs
  • antimicrobials
    • amphotericin B, cephalosporins, nitrofurantoin, minocycline
  • chemotherapeutics
    • bleomycin, busulfan, chlorambucil, doxorubicin, trastuzumab
  • interferons
  • methotrexate
  • amiodarone
  • phenytoin
Miscellaneous
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Article information

rID: 63188
Section: Gamuts
Synonyms or Alternate Spellings:
  • Secondary organizing pneumonia

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