Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

692 results found
Article

Transcatheter arterial chemoembolisation

Transcatheter arterial chemoembolisation (TACE), also known as transarterial chemoembolisation, is a minimally-invasive method of administering chemotherapy directly to a liver tumor via a catheter under digital subtraction angiography (DSA). The chemoembolic agent may be delivered as a mixture ...
Article

Limy bile

Limy bile stands for the presence of a viscous substance in the dependent parts of the gallbladder and/or bile ducts, almost entirely composed of calcium carbonate, and therefore highly radiopaque. Terminology The terms limy bile and calcium milk gallbladder can be used interchangeably for inc...
Article

Focal hepatic hot spot sign

The focal hepatic hot spot sign, also known as the hot quadrate sign can be seen on technetium 99m sulfur colloid scans of the liver and spleen, as well as CT studies. Radiographic features It occurs as a focal area of increased radiopharmaceutical uptake, or iodinated contrast accumulation, i...
Article

Double barrel sign (disambiguation)

Double barrel sign is an imaging appearance of two lumens adjacent to each other. It can be seen in: dilated bile duct adjacent to portal vein double barrel aorta: aortic dissection double barrel esophagus: esophageal dissection
Article

Somatostatinoma

Somatostatinomas are a rare type of neuroendocrine tumor.  Epidemiology  They form up to ~1% of all gastroenteropancreatic endocrine neoplasms.  Associations multiple endocrine neoplasia type 1 (MEN1) 2 von Hippel Lindau (vHL) disease 2 duodenal somatostatinoma: neurofibromatosis type 1 (N...
Article

Hepatobiliary system

The hepatobiliary system consists of the: liver biliary tree (both intra- and extra-hepatic) gallbladder The pancreas is included by some. 
Article

CT cholangiography (protocol)

CT cholangiography is a technique of imaging the biliary tree with the usage of hepatobiliary excreted contrast. It is useful in delineating biliary anatomy, identifying a bile leak or looking for retained gallstones within the biliary system. Indications Second-line test (after ultrasound) wh...
Article

Pancreatic intraepithelial neoplasia

Pancreatic intraepithelial neoplasia (PanIN) is a precursor lesion to pancreatic ductal adenocarcinoma, but the frequency at which this transition occurs is unknown.  Epidemiology Increasing incidence with age 1. Risk factors: obesity pancreatic lipomatosis 3 Pathology Mostly flat lesions ...
Article

Pancreatic atrophy

Pancreatic atrophy is non-specific and is common in elderly patients, although in younger patients it can be a hallmark of pathology. Most commonly it is associated with aging, obesity and end-stage chronic pancreatitis.  It occurs principally with fatty replacement of the pancreas (pancreatic ...
Article

Endoscopic retrograde cholangiopancreatography

Endoscopic retrograde cholangiopancreatography (ERCP) is a diagnostic and interventional procedure technique using both endoscopy and fluoroscopy for examination and intervention of the biliary tree and pancreatic ducts. It is typically performed by doctors with endoscopic qualifications (e.g. g...
Article

Gallstone pancreatitis

Gallstone pancreatitis refers to pancreatitis caused by gallstones, specifically distal choledocholithiasis. Gallstones are the cause for 35-40% of acute pancreatitis but this number has a wide regional variance.  Epidemiology Gallstone pancreatitis has a higher incidence in women (compared to...
Article

Acute necrotic collection

Acute necrotic collections (ANCs) are an early, local complication of necrotizing pancreatitis. Terminology The following are the latest terms according to the updated Atlanta classification to describe fluid collections associated with acute pancreatitis 1,2: fluid collections in interstitia...
Article

Acute peripancreatic fluid collection

Acute peripancreatic fluid collections (APFC) are an early complication of acute pancreatitis that usually develop in the first four weeks. After four weeks, the term pseudocysts is used. The absence of necrosis differentiates APFCs from acute necrotic collections (ANC), that is, APFCs occur in ...
Article

Portal vein embolization

Portal vein embolization (PVE) is a technique used to selectively occlude the blood supply to one of the liver lobes, diverting portal blood flow to the other lobe, the future liver remnant (FLR). This diversion will increase the size of the post-hepatectomy future liver remnant, which improves...
Article

Interstitial edematous pancreatitis

Interstitial edematous pancreatitis is one of the two subtypes of acute pancreatitis. It is normally referred to as "acute pancreatitis" or "uncomplicated pancreatitis" in day-to-day use. Please refer to the article on acute pancreatitis for further details. 
Article

Gallbladder inflammatory polyps

Gallbladder inflammatory polyps are a benign subtype of gallbladder polyps, representing ~10% of all polyps. They appear as a result of chronic inflammation (chronic cholecystitis).  For further details, please refer to the parental article on gallbladder polyps.  Pathology Gallbladder inflam...
Article

Gallbladder hydrops

Gallbladder hydrops or mucocele 5 refers to marked dilatation of the gallbladder due to chronic obstruction of the cystic duct resulting in accumulation of sterile non-pigmented mucin. Clinical presentation Abdominal pain with palpable gallbladder without any signs of infection. In an asymptom...
Article

Hyperattenuating gallbladder (differential)

A hyperattenuating gallbladder may occur from a number of different etiologies: sludge in the gallbladder vicarious excretion of intravenous contrast (iodinated contrast or gadolinium contrast) hyperconcentrated bile noncalcified gallstones medications I.e ceftriaxone associated gallbladder...
Article

Beta catenin mutated hepatic adenoma

Beta catenin mutated hepatic adenomas are a genetic and pathologic subtype of hepatic adenoma. Their appearance and prognosis are different from other subtypes. Epidemiology They are the least common subtype of hepatic adenoma (10-15%). They occur more frequently in men and are associated with...
Article

HNF 1 alpha mutated hepatic adenoma

HNF 1 alpha mutated hepatic adenomas are a genetic and pathologic subtype of hepatic adenoma. Their appearance and prognosis are different from other subtypes. Epidemiology They are the second most common (30-35%) hepatic adenoma after the inflammatory subtype. They occur only in female patien...
Article

Inflammatory hepatic adenoma

Inflammatory hepatic adenomas are a genetic and pathological subtype of hepatic adenoma. Their appearance and prognosis is different than other subtypes and they have the highest incidence of hemorrhage amongst hepatic adenoma subtypes. Epidemiology Inflammatory hepatic adenomas are the most c...
Article

Lemmel syndrome

Lemmel syndrome is defined as obstructive jaundice caused by a periampullary duodenal diverticulum compressing the intrapancreatic common bile duct with resultant bile duct dilatation. Clinical presentation Patients may present with recurrent episodes of jaundice, pancreatitis and/or cholangit...
Article

Ectopic intracaval liver

Ectopic intracaval liver is a very rare congenital abnormality of the liver in which a part of the liver, not contiguous with the liver proper, lies within the inferior vena cava (IVC).  Ectopic hepatic lobes elsewhere have been described rarely as congenital abnormalities, but a location withi...
Article

Duct penetrating sign (pancreas)

Duct penetrating sign is a radiographic sign that can be useful in differentiating between focal pancreatitis (inflammatory pancreatic mass) from pancreatic carcinoma. A positive sign is when a mass is penetrated by an unobstructed pancreatic duct; this makes focal pancreatitis the most likely ...
Article

Non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD), also known as metabolic associated fatty liver disease, occurs when fat is deposited into hepatocytes without a known cause (such as with alcoholic fatty liver disease). The deposition of fat may lead to hepatic inflammation (hepatitis) and even eventua...
Article

Supradiaphragmatic liver

Supradiaphragmatic liver has been reported as a very rare variant in liver morphology.  In this variant, liver tissue extends into the right hemithorax through an opening in the right hemidiaphragm. The tissue is connected to the right hepatic lobe by a pedicle. In one report, the caudate lobe ...
Article

Hepatitis C virus

Hepatitis C virus (HCV) is an RNA virus and a member of the Flaviviridae family. It is a risk factor for the development of hepatocellular carcinoma (HCC). Pathology Route of transmission The most common route of transmission is through blood products and contaminated needles. Unprotected sex...
Article

Hepatitis B virus

Hepatitis B virus (HBV) is a circular DNA virus endemic in many parts of the world. It is a risk factor for the development of hepatocellular carcinoma (HCC). Clinical presentation Acute HBV infection is most often subclinical and asymptomatic. Symptomatic patients (~33%) may experience fever,...
Article

Autoimmune hepatitis

Autoimmune hepatitis (AIH) (plural: autoimmune hepatitides) is a rare type of chronic hepatitis, currently classified as "type 1" or "type 2". It may eventually lead to cirrhosis. The role of imaging is primarily to exclude other diagnoses and evaluate for complications. Epidemiology It may oc...
Article

Cholangiocarcinoma (staging)

Cholangiocarcinoma staging is most commonly classified using the TNM staging systems of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC), which starting 1 January 2018 is according to its 8th edition. There are separate systems depending on whether the ...
Article

Okuda staging system

The Okuda staging system was an advance on earlier hepatocellular (HCC) staging classifications, in that it incorporated both cancer-related variables and liver function related variables to determine prognosis 1: disease involving >50% of hepatic parenchyma ascites albumin ≤3 mg/dL bilirubi...
Article

Liver cancer (BCLC staging)

Barcelona clinic liver cancer (BCLC) staging uses a set of criteria to guide the management of patients with hepatocellular carcinoma (HCC). The classification takes the following variables into account 1,2: performance status (PS)  Child-Pugh score radiologic tumor extent tumor size multi...
Article

Hepatocellular carcinoma (staging)

Hepatocellular carcinoma staging classifications supersede the typical TNM staging system seen in most other epithelial cancers, as the TNM staging system has been found to not be as prognostically useful for stratification of patients with hepatocellular carcinoma. Several substitute staging sy...
Article

Hepatocellular carcinoma (surveillance)

Hepatocellular carcinoma surveillance programs have been adopted by some health systems in attempts to effect an early diagnosis of hepatocellular carcinoma in high-risk populations.  Rationale The idea behind hepatocellular carcinoma screening, as with any screening program, is to detect clin...
Article

Type I choledochal cyst

Type I choledochal cysts appear as a fusiform or cystic dilatation of the extrahepatic biliary system (common bile duct +/- common hepatic duct). Epidemiology Although uncommon in Western countries (1:100,000 to 1:150,000), they are the most common type of biliary cyst. Their prevalence may be...
Article

Hepatic solitary fibrous tumor

Hepatic solitary fibrous tumors are rare mesenchymal tumors. Terminology Historically, hepatic solitary fibrous tumors were known as hepatic hemangiopericytomas, however this term has now been abandoned.  Epidemiology Fewer than 60 cases of hepatic solitary fibrous tumor have been reported i...
Article

Bile duct wall thickening (differential)

Thickening of the bile duct wall can stem from a variety of etiologies. Radiographic features Ultrasound bile duct wall thickening bile duct walls are typically not visible when normal possible narrowing of the ducts with obstruction possible secondary signs of cholangitis, including debri...
Article

Bile duct dilatation

Bile duct dilatation refers to the dilatation of intrahepatic or extrahepatic bile ducts. Clinical presentation Variable, depending on the underlying cause, but usually: right upper quadrant pain jaundice Radiographic features Ultrasound Harmonic imaging is useful when assessing the bilia...
Article

Agenesis of the left hepatic lobe

Agenesis of the left hepatic lobe is a rare variation in liver anatomy. It is clinically asymptomatic and discovered during imaging or surgery. Radiographic features absence of the left hepatic lobe (left of the falciform ligament, Couinaud segments 2 and 3) absence of left hepatic artery, le...
Article

Agenesis of the right hepatic lobe

Agenesis of the right hepatic lobe is a rare variation in liver anatomy. Radiographic features absence of the right hepatic lobe absence of right hepatic artery, right portal vein, and right hepatic biliary system compensatory hypertrophy of the left hepatic lobe and caudate lobe possible r...
Article

Hepatic myeloid sarcoma

Hepatic myeloid sarcomas, also referred to as hepatic granulocytic sarcoma or hepatic chloromas, are rare neoplasms comprised of myeloid precursor cells happening in the liver. They are a unique presentation of acute myeloid leukemia (AML).  Please refer to the main article on myeloid sarcoma/c...
Article

Hepatobiliary contrast agents and LI-RADS

LI-RADS (Liver Imaging Reporting and Data System) is both a set of standardized terminology and a classification system for imaging findings in liver lesions. The LI-RADS score for a liver lesion is an indication of its relative risk for hepatocellular carcinoma (HCC). The classification system ...
Article

Idiopathic non-cirrhotic portal hypertension

Idiopathic non-cirrhotic portal hypertension is the clinical diagnosis of exclusion featuring portal hypertension without hepatic cirrhosis, vascular obstruction, schistosomiasis, or a variety of other chronic liver diseases. Terminology Prior terms for this entity include non-cirrhotic portal...
Article

Focal gallbladder wall thickening (differential)

Focal gallbladder wall thickening is an imaging finding that includes both benign and malignant etiologies. cholecystoses cholesterolosis adenomyomatosis masses gallbladder polyps gallbladder carcinoma: look for infiltration into adjacent organs, metastases, lymphadenopathy, bile duct dil...
Article

Abdominal and pelvic anatomy

Abdominal and pelvic anatomy encompasses the anatomy of all structures of the abdominal and pelvic cavities. This anatomy section promotes the use of the Terminologia Anatomica, the international standard of anatomical nomenclature. 
Article

Diffuse hepatic steatosis (grading)

Grading of diffuse hepatic steatosis on ultrasound has been used to communicate to the clinician about the extent of fatty changes in the liver.  Grading grade I: diffusely increased hepatic echogenicity but periportal and diaphragmatic echogenicity is still appreciable grade II: diffusely in...
Article

Paraumbilical veins

The paraumbilical veins are small veins around the falciform ligament that drain venous blood from the anterior part of the abdominal wall and diaphragm directly into the liver and communicate with other anterior abdominal wall veins 1,2.  Gross anatomy The superior vein of Sappey drains the u...
Article

Secondary hepatic involvement with lymphoma

Secondary hepatic involvement with lymphoma (secondary hepatic lymphoma) is common, much more so than primary hepatic lymphoma.  Clinical presentation Hepatomegaly with deranged liver function tests is the most common presentation. Jaundice is common. Rarely, patients may present with acute li...
Article

Hyalinised hepatic hemangioma

Hyalinised hepatic hemangiomas, also known as sclerosing/sclerosed hepatic hemangiomas, are a rare variant of hepatic hemangioma. Because of their unusual imaging features, they cannot be reliably differentiated from a malignant tumor without a biopsy. Liver capsular retraction is a common featu...
Article

Acute hepatitis

Acute hepatitis (plural: acute hepatitides) occurs when the liver suffers an injury with a resulting inflammatory reaction. The cause of the injury can happen in multiple different ways, and imaging findings are often non-specific. Acute hepatitis is a clinical diagnosis and a normal imaging app...
Article

Hepatic pseudolesion near falciform ligament

Hepatic pseudolesions near the falciform ligament show abnormal attenuation without mass effect. They may be seen on contrast-enhanced CT scans as either a region of high or low attenuation relative to the rest of the liver. They are typically located in the medial segment of the left lobe of th...
Article

MELD score

The MELD score (Model for End-stage Liver Disease) is a classification used to grade liver dysfunction in preparation for liver transplantation. The score has prognostic value in terms of three month mortality and certain complications. The components of the score are: serum creatinine (mg/dl)...
Article

Cystic hepatic metastases

Cystic hepatic metastases are included in the differential for new cystic liver lesions. The internal cystic component may represent necrosis as the tumor outgrows its hepatic blood supply, or it may represent a mucinous component, similar to the primary tumor. The liver and lungs are the most ...
Article

Hepatic adenomatosis

Hepatic adenomatosis is the presence of numerous, more than 10 and up to 50, hepatic adenomas. It is a rare disorder, best characterized with MRI. Epidemiology Patients with hepatic adenomatosis do not necessarily have the classic risk factors associated with the development of hepatic adenoma...
Article

Meglumine iotroxate (Biliscopin)

Meglumine iotroxate (BiliscopinTM) is an iodinated, intravenous contrast agent that is preferentially excreted into the biliary tree and is used in CT intravenous cholangiography. The typical dose is 100 mL Biliscopin (105 mg meglumine iotroxate/mL; 5.0 g iodine), which is administered via slow...
Article

Hepatic angiosarcoma

Hepatic angiosarcoma is a rare malignancy but is still the third most common primary liver tumor. They have a variable appearance on both CT and MRI, reflecting the pleomorphic histological nature. Prognosis is very poor, with survival uncommon beyond one year from diagnosis.  Terminology Hepa...
Article

Magnetic resonance cholangiopancreatography (MRCP)

Magnetic resonance cholangiopancreatography (MRCP) is a non-invasive imaging technique to visualize the intra and extrahepatic biliary tree and pancreatic ductal system. It can provide diagnostically-equivalent images to ERCP and is a useful technique in high risk patients to avoid significant ...
Article

Hepatic siderotic nodules

Hepatic siderotic nodules are a type of regenerative nodule formed in a cirrhotic liver. They occur in hepatic hemosiderosis. The nodules have an increased iron content compared with other regenerative nodules. They may be non-dysplastic or dysplastic. Pathology The reason why these nodules co...
Article

LR2 cirrhosis-associated nodule

LR2 cirrhosis-associated nodules are defined as "probably benign" according to the LI-RADS classification system. They are a common finding in a cirrhotic liver and do not need to be mentioned in the report.  Radiographic features The nodule must demonstrate all of the following: diameter <20...
Article

LI-RADS

Liver Imaging Reporting and Data System (LI-RADS) is both a set of standardized terminology and a classification system for imaging findings in liver lesions. The LI-RADS score for a liver lesion is an indication of its relative risk for hepatocellular carcinoma (HCC). The classification system...
Article

Three line sign (common bile duct)

The three line sign refers to an MRI term that describes the appearance of roundworm Ascaris lumbricoides within the CBD lumen which appears as two hypointense lines representing the worm walls and hyperintense center which represents the worm gut. See also biliary ascariasis
Article

Biliary ascariasis

Ascariasis is the commonest helminthic infection worldwide and estimated to affect nearly 1 billion people (25% of the population). The disease is transmitted by Ascaris lumbricoides which belongs to the nematode family (roundworms). Lifecycle Infection occurs by ingestion of contaminated food...
Article

Hepatic leiomyosarcoma

Hepatic leiomyosarcomas are rare primary malignant tumors derived from smooth muscle cells in the liver. Epidemiology Hepatic leiomyosarcoma is rare 1. An equal sex distribution and a broad age range (5 months-66Y) has been reported. Some have suggested an associated with AIDS 2. Pathology T...
Article

Confluent hepatic fibrosis

Confluent hepatic fibrosis is a possible result of chronic injury to the liver, most commonly from cirrhosis or hepatic vascular injury. Epidemiology It most commonly occurs in patients with alcoholic cirrhosis (up to 15% of advanced cases), autoimmune hepatitis and primary sclerosing cholangi...
Article

Pancreas transplant

A pancreas transplant is a procedure in which a donor pancreas is transplanted to a recipient. The donor pancreas is typically cadaveric, but may rarely be a segment from a living donor 1. The transplant is meant to establish normoglycemia in patients with diabetes mellitus, typically type 1, th...
Article

Portopulmonary hypertension

Portopulmonary hypertension (POPH/PPHTN) refers to pulmonary artery hypertension that develops in the setting of portal hypertension (with or without underlying liver disease). It falls under group 1.4 of the Dana point 2008 pulmonary hypertension classification system. Epidemiology The preval...
Article

Frey procedure

The Frey procedure is a type of pancreaticojejunostomy designed to treat chronic pancreatitis. The fundamental technique is similar to the Puestow procedure, with a lateral incision of the pancreatic duct from an anterior approach, and then a side-to-side anastomosis between the pancreas and a ...
Article

Extrahepatic portal vein obstruction

Extrahepatic portal vein obstruction is the most common cause of non-cirrhotic portal hypertension in children and young adults in developing countries. It may or may not extend into the intrahepatic portal vein. Clinical presentation It usually occurs in children and young adults, presenting ...
Article

Pseudolipoma of the Glisson capsule

Pseudolipomas of the Glisson capsule are an uncommon developmental anomaly where a piece of colonic epiploic fat becomes ectopically located within the liver capsule. Radiographic features CT well-circumscribed fat attenuation (-20 to -70 HU) nodule at the liver surface it can sometimes have...
Article

Spindle cell hepatocellular carcinoma

Spindle cell hepatocellular carcinoma, also called sarcomatoid hepatocellular carcinoma, is a rare variant of hepatocellular carcinoma (HCC). These patients are reported to have low or normal AFP levels, otherwise risk factors and clinical presentation are similar to typical hepatocellular carci...
Article

Hepatic neuroendocrine tumor

Primary hepatic neuroendocrine tumors (carcinoids) is an extremely rare type of neuroendocrine tumor, with somewhere between 60-90 cases reported in the literature. Metastatic neuroendocrine tumor from the gastrointestinal tract to the liver is far more common. Clinical presentation Some patie...
Article

MR liver iron quantification

MR liver iron quantification is a non-invasive means of measuring liver iron concentration, a key indicator in the management of patients with hemochromatosis (primary or secondary). Advantages Apart from being non-invasive, sampling occurs in a large cross-section of the liver, as opposed to ...
Article

Hepatoduodenal ligament

The hepatoduodenal ligament is a peritoneal ligament of lesser omentum containing the portal triad 1.  Gross anatomy The hepatoduodenal ligament is a thickening of the right edge of the lesser omentum and forms the anterior margin of the epiploic foramen. It extends from the porta hepatis to t...
Article

Left triangular ligament of the liver

The left triangular ligament is a peritoneal suspensory ligament of the liver. It is formed by the fusion of the superior and inferior reflections of the coronary ligament. It is shorter than the right triangular ligament and does not separate the left subphrenic space from the subhepatic space.
Article

Right triangular ligament of the liver

The right triangular ligament is a peritoneal suspensory ligament of the liver. It is formed by the fusion of the superior and inferior reflections of the right coronary ligament. It is longer than the left triangular ligament and compartmentalises the right subphrenic and subhepatic spaces.
Article

T tube cholangiogram

T-tube cholangiograms are a fluoroscopic study performed in the setting of hepatobiliary disease.  This technique has been largely superseded by MRCP and ERCP. Typically a T-shaped tube is left in the common bile duct at the time of surgery (e.g. cholecystectomy) and allows for exploration of t...
Article

Imaging in liver transplantation

Imaging in liver transplantation is aimed to evaluate donor and recipient for successful transplantation and its outcome. Pre-transplant evaluation Donor volume of liver parenchymal disease (diffuse or focal) vascular anatomy arterial variations venous variations biliary anatomy Recipie...
Article

Kasai classification

Kasai classification is used to describe the three main anatomical types of biliary atresia. Classification type I: obliteration of common bile duct (patent cystic and common hepatic duct) type II IIa: obliteration of common hepatic duct (patent cystic and common bile duct), sometimes with a...
Article

Cystic lesions of the liver (differential)

Cystic lesions of the liver carry a broad differential diagnosis: simple cysts simple hepatic cyst biliary hamartoma Caroli disease adult polycystic liver disease ciliated hepatic foregut duplication cyst 6 infectious: inflammatory conditions hepatic abscess pyogenic hepatic abscess am...
Article

Radioembolization

Radioembolization is the delivery of radioactive microspheres to cancers using an endovascular approach. It is often performed as an outpatient procedure.  Indications hepatocellular carcinoma 2 hepatic metastases from colorectal carcinoma Contraindications Absolute contraindications exces...
Article

Revised Atlanta classification of acute pancreatitis

The Revised Atlanta classification of acute pancreatitis from 2012 is an international multidisciplinary classification of the severity of acute pancreatitis, updating the 1992 Atlanta classification. The worldwide consensus aims for an internationally agreed-upon classification of acute pancre...
Article

Komi classification of bile duct cysts

Komi classification of bile duct cysts divides anomalous union of the pancreatico-bile ducts (AUPBD) into three types based on the angle of union of the ducts 1. Classification type I: union of the ducts at a right angle to each other type Ia: without dilatation or  type Ib: with dilatation ...
Article

Cantlie line

Cantlie line is a vertical plane that divides the liver into left and right lobes creating the principal plane used for hepatectomy. It extends from the inferior vena cava posteriorly to the middle of the gallbladder fossa anteriorly. It contains the middle hepatic vein, which divides the liver...
Article

Pseudocirrhosis

Pseudocirrhosis is a radiological term used to convey the imaging findings of cirrhosis, but emphasize that it occurs in the setting of hepatic metastases. It is most commonly reported following chemotherapeutic treatment of breast cancer metastases, although has also been reported before treatm...
Article

Niemann-Pick disease type C

Niemann-Pick disease type c (NPD-C or just NPC) is an autosomal recessive lysosomal storage disorder classed under Niemann-Pick disease on account of clinical similarities, namely hepatosplenomegaly and variable involvement of the central nervous system.  Epidemiology NPD-C is inherited as an ...
Article

Niemann-Pick disease

Niemann-Pick disease (NPD) is actually a collection of a number of distinct autosomal recessive lysosomal storage diseases. They are divided into two groups of two based on the underlying metabolic deficiency: deficiency of acid sphingomyelinase 1,3,4 Niemann-Pick disease type A (NPD-A) sever...
Article

Gallbladder agenesis

Agenesis of the gallbladder describes the rare congenital absence of the gallbladder. Epidemiology overall incidence is estimated <0.1% (range 0.04-0.1%) gender:  reported 3:1 female predominance of symptomatic cases equivalent gender distribution in autopsy cases ...
Article

Gallbladder triplication

Gallbladder triplication is an extremely rare anomaly. There are three types of gallbladder triplication are described according to the number of cystic duct and their insertion: Three gallbladders and three cystic ducts which unite to form a common cystic duct before joining the common bile du...
Article

Contrast-enhanced ultrasound

Contrast-enhanced ultrasound (CEUS) involves the administration of intravenous contrast agents consisting of microbubbles/nanobubbles of gas. Usecases liver hepatic metastasis cystadenoma/cystadenocarcinoma cholangiocarcinoma hepatocellular carcinoma hepatic adenoma focal nodular hyperpl...
Article

Gastroduodenal artery

The gastroduodenal artery (GDA) is a terminal branch of the common hepatic artery which mainly supplies the pylorus of the stomach, proximal duodenum, and the head of the pancreas. Due to its proximity to the posterior wall of the first part of the duodenum, the gastroduodenal artery is one of t...
Article

Hepatic artery proper

The hepatic artery proper, also known as the proper hepatic artery (PHA), is the continuation of the common hepatic artery after it gives off the gastroduodenal artery. Just prior to the porta hepatis it divides into the left and right hepatic arteries. Gross anatomy Course The hepatic artery...
Article

Posterior right subhepatic space

The posterior right subhepatic space (also known as the hepatorenal fossa or Morison pouch) separates the liver from the right kidney. It is a potential space that is not filled with any fluid in normal conditions. Gross anatomy The posterior right subhepatic space is a subcompartment of the s...
Article

Jaundice

Jaundice refers to a clinical sign of hyperbilirubinemia (serum bilirubin >2.5 mg/dL) which has many causes. It is often a clue to a diagnosis. It can be largely divided into two types: non-obstructive, i.e. prehepatic and hepatic causes obstructive, i.e. posthepatic causes Imaging has a majo...

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.