Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

1,385 results found
Article

Thurstan Holland fragment

The Thurstan Holland fragment (or Thurstan Holland sign) is an eponymous radiological sign depicting a triangular portion of the metaphysis remaining with the epiphysis in a physeal fracture. This fragment indicates that a type 2 Salter-Harris fracture has occurred 1. History and etymology It...
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Multiple synostoses syndrome

Multiple synostoses syndrome (SYNS), proximal symphalangism (SYM), tarsal-carpal coalition (TCC) syndrome, stapes ankylosis with broad thumbs and toes (SABTT), and brachydactyly B2 (BDB2) are overlapping autosomal dominant conditions united by typically displaying ankylosis of the proximal inter...
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Chrispin-Norman scoring system for cystic fibrosis

The Chrispin-Norman score is used to provide a summative assessment of structural lung changes in patients with cystic fibrosis on plain chest radiographs. It is useful to monitor disease progression or treatment response and can be used to compare between different patients in research studies...
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Ductus arteriosus

The ductus arteriosum (DA) (or arteriosus) is the thick short conduit for blood to bypass the non-ventilated lungs in the fetus. It is located between and connects the proximal left pulmonary artery and the undersurface of the aortic arch distal to the origin of the last branch of the arch, at t...
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Fossa ovalis

The fossa ovalis is the small oval depression in the interatrial septum at the site of the closed foramen ovale, which closes once fetal circulation ceases in the first few minutes of postnatal life. It represents the overlapping primary and secondary septa of the interatrial septum. It has a se...
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Intestinal failure

Intestinal failure is when a patient's native bowel is unable to digest and absorb the food, electrolytes, and fluids needed for normal growth and development.  Clinical presentation This often includes intractable diarrhea, weight loss, dehydration, electrolyte imbalance, and malnutrition. P...
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Foramen ovale (cardiac)

The foramen ovale (or ovalis) is the opening in the interatrial septum in the fetal heart that allows blood to bypass the right ventricle and non-ventilated lungs, shunted from the right atrium to the left atrium. Specifically it represents the opening between the upper and lower portions of th...
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Hypertrophic pyloric stenosis (ultrasound measurements mnemonic)

Hypertrophic pyloric stenosis can be characterized on ultrasound by the measurements of the hypertrophic muscle. Although the criteria can vary from publication to publication, an easy way to keep in mind the values is using a mnemonic which relies upon remembering the first digits of the number...
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Taussig-Bing anomaly

Taussig-Bing anomaly is a rare congenital heart malformation and is one of the variants of double outlet right ventricle. It consists of transposition of the aorta to the right ventricle and malposition of the pulmonary artery with subpulmonary ventricular septal defect. History and etymology ...
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Vitamin B1

Vitamin B1 (thiamine) is a water-soluble vitamin, that is part of the vitamin B complex, and is an important coenzyme for two reactions in the citric acid cycle (Kreb cycle). It therefore is vital for cellular ATP production, particularly in the central nervous system. Terminology Thiamine is ...
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Vitamin C

Vitamin C (L-ascorbic acid) is a water soluble vitamin that is a coenzyme for the formation of the structure protein collagen, particularly creating cross-linking of collagen fibers which greatly increases its tensile strength. It also acts as an antioxidant. Vitamin C is one of the hematinics. ...
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Vitamin K

Vitamin K is not a single compound but a family of fat-soluble vitamins essential for normal blood-clotting function and comprises two vitamers that are found naturally: phytomenadione (also known as phylloquinone or K1) and menaquinone (or K2). Menaquinone (K2) is synthesized by normal flora i...
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Vitamin E

Vitamin E (the tocopherols) are a group of fat-soluble vitamins that act as antioxidants. Vitamin E are also hematinics. hypovitaminosis E is rarely seen outside premature infants hypervitaminosis E is extremely rare as the toxicity of vitamin E is low except in chronic (usually >1 year) high ...
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Febrile infection-related epilepsy syndrome (FIRES)

Febrile infection-related epilepsy syndrome (FIRES) is a severe postinfectious neurological disorder that presents with new-onset refractory status epilepticus in a previously normal child (or less commonly adult) after a febrile illness. Terminology FIRES has received several names in the lit...
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Central tegmental tract T2 hyperintensity

High T2 signal of the central tegmental tract, which connects the red nucleus and inferior olivary nucleus, is an uncommon finding typically encountered in early childhood.  The central tegmental tract refers mainly to the extrapyramidal tracts connecting between the red nucleus and the inferio...
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Anatomy curriculum

The anatomy curriculum is one of our curriculum articles and aims to be a collection of articles that represent the core anatomy knowledge for radiologists and imaging specialists. General anatomy Neuroanatomy Head and neck anatomy Thoracic anatomy Abdominal and pelvic anatomy Spinal anat...
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Small bowel atresia

Small bowel atresia corresponds to malformations where there is a narrowing or absence of a portion of the small bowel, which includes: duodenal atresia jejunal atresia ileal atresia
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Omega sign (disambiguation)

The omega sign can refer to a number of different anatomical structures or signs: omega sign (epiglottitis) omega sign (hand bump on the precentral gyrus)
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Terminal myelocystocele

Terminal myelocystoceles are an uncommon form of spinal dysraphism representing marked dilatation of the central canal of the spinal cord, herniating posteriorly through a dorsal spinal defect. The result is a skin-covered mass in the lower lumbar region, consisting of an ependyma-lined sac.  E...
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Chondrolysis

Chondrolysis, also known as acute cartilage necrosis, represents acute cartilage destruction of the femoral head. It is one of the complications that are specifically associated with slipped capital femoral epiphysis (SCFE). It may also be associated with infection, specifically septic arthritis...
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Storage disorders

Storage disorders comprise a bewildering collection of inherited metabolic conditions which share the accumulation of a metabolite within various cells in the body due to dysfunction of specific enzymes or transport proteins. Accumulation of metabolites eventually results in cellular and/or orga...
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Neuronal ceroid lipofuscinosis

Neuronal ceroid lipofuscinoses (NCLs), occasionally known collectively as Batten disease, are a group of genetic neurodegenerative disorders of childhood in which there is excessive accumulation of lipofuscin. Terminology The use of Batten disease as an umbrella term for neuronal ceroid lipofu...
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Pediatric urinary tract infection (NICE guideline)

The British National Institute for Health and Care Excellence (NICE) published the “Urinary tract infection in under 16s: diagnosis and management” in 2007 as a guideline for pediatric urinary tract infection (UTI) management, including imaging, prophylaxis and follow-up 1.  This article intend...
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Intestinal nonrotation

Intestinal nonrotation is a congenital anomaly of the intestines that results in the small bowel occupying the right side of the peritoneal cavity and the colon predominantly on the left. It is sometimes thought of as a subtype of intestinal malrotation. Epidemiology Nonrotation is estimated ...
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FATCO syndrome

FATCO syndrome consists: FA: fibular aplasia TC: tibial campomelia O: oligosyndactyly It is a syndrome of unknown genetic basis and inheritance with variable expressivity and penetrance 1,2. Radiographic features Associated anomalies in FATCO syndrome include 3: anterolateral bowing of th...
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Rickets (mnemonic)

A mnemonic to remember the radiological features of rickets is: RICKETS Mnemonic R: reaction of the periosteum I: indistinct cortex C: coarse trabeculation K: knees, wrists and ankles mainly E: epiphyseal plates widened and irregular  T: tremendous metaphysis S: spur (metaphyseal)​
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Innominate artery compression syndrome

Innominate artery compression syndrome, also known as brachiocephalic artery compression syndrome, is a rare cause of tracheal stenosis that occurs in the pediatric population. It is due to abnormal compression of the anterior aspect of the trachea as the brachiocephalic artery crosses it. Diag...
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Melanotic neuroectodermal tumor of infancy

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented tumor that primarily affects the calvaria or facial skeleton of children, typically during infancy. It is usually a benign tumor, albeit locally aggressive. Epidemiology Most cases are diagnosed during infancy, usually withi...
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Slipped upper femoral epiphysis (summary)

This is a basic article for medical students and other non-radiologists Slipped upper femoral epiphysis (SUFE), also known as a slipped capital femoral epiphysis (SCFE),  is a relatively common condition affecting the physis of the proximal femur in adolescents. It is one of commonest hip abnor...
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Physeal fracture

Physeal fractures (also called Salter-Harris fractures) are important childhood fractures that involve the physis (physeal/growth plate). They are relatively common and important to differentiate from other injuries because the involvement of the physis may cause premature closure resulting in l...
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Salter-Harris type I fracture

Salter-Harris type I fractures are relatively uncommon injuries that occur in children. Salter-Harris fractures are injuries where a fracture of the metaphysis or epiphysis extends through the physis. Not all fractures that extend to the growth plate are Salter-Harris fractures. Radiographic fe...
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Fracture translation

Fracture translation (also called translocation) describes the movement of fractured bones away from each other. In some cases, people will just use the term displacement to describe translation. However, displacement should really be used as a broad term that refers to angulation, translation a...
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Parapagus

Parapagus twins are conjoined twins that lie side-by-side with ventrolateral fusion.  This type of conjoined twins usually shares the umbilicus, abdomen, and pelvis. The conjoined pelvis may have a single symphysis pubis and one or two sacra.  The lower gastrointestinal tract (single colon and...
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Cephalopagus

Cephalopagus twins are a rare type of conjoined twins. They are fused from the vertex to the umbilicus. They share a common cranium with either one composite face or two faces on opposite sides of the conjoined head. The thoraces are fused with fusion of liver, heart, and the upper gastrointest...
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Rachipagus

Rachipagus twins are an extremely rare type of conjoined twins. They are joined in the dorsal aspect and face away from each other. Fusion of the occiput with varying segments of the vertebral column may occur, resulting in the sharing of the spinal cords. The fusion terminates above the sacrum...
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Craniopagus

Craniopagus twins are conjoined twins that are fused at any part of the skull, except the face, foramen magnum, skull base and the vertebral column. The fused structures are most often the cranium, meninges, and dural venous sinuses. Brains tend to be separate; however, they may be connected by...
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Thoracopagus conjoined twins

Thoracopagus conjoined twins are, as the name suggests, conjoined twins united at their thorax. Thoracopagus and thoraco-omphalopagus form the most common forms of conjoined twins 3. Fusion is typically face-to-face, at the upper thorax to the umbilicus with a common sternum, diaphragm, and upp...
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Crista galli

The crista galli is a thick, midline, smooth triangular process arising from the superior surface of the ethmoid bone, projecting into the anterior cranial fossa. It separates the olfactory bulbs, which lie on either side of it in the olfactory fossae of the cribriform plate. It serves as an ant...
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Neonatal abdominal radiograph (supine view)

AP supine radiograph for neonates is a mobile examination performed on the neonatal unit. It can be taken as a standalone projection or as part of a series including a left lateral decubitus x-ray in cases of suspected perforation.  Patient position the patient is supine, lying on their bac...
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Chronic recurrent multifocal osteomyelitis

Chronic recurrent multifocal osteomyelitis (CRMO) is an idiopathic inflammatory bone disorder seen primarily in children and adolescents. It is often a diagnosis of exclusion once underlying infection and neoplasia have been ruled out. However, there are some cases in which lesion location and m...
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Poliomyelitis-like syndrome

Poliomyelitis-like syndrome, or polio-like paralysis, is an uncommon form of myelitis that presents similar to polio, due to non-poliovirus pathologies which selectively involve the anterior horn cells of the spinal cord and result in an anterior horn syndrome. Although it usually has an infecti...
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Spleen size (pediatric)

The spleen size varies with a child's age. The three numbers below represent the 10th percentile, median, and 90th percentile for the long axis of the spleen (cm) 1-3: 0-3 months: (3.3, 4.5, 5.8 cm) 3-6 months: (4.9, 5.3, 6.4 cm) 6-12 months: (5.2, 6.2, 6.8 cm) 1-2 years: (5.4, 6.9, 7.5 cm)...
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Epilepsy

Epilepsy is a common neurological disorder that is characterized by a predisposition to having epileptic seizures. Epilepsy is defined by the International League Against Epilepsy (ILAE) as 1: at least two or more unprovoked (or reflex) seizures occurring more than 24 hours apart; or on...
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Potter syndrome (mnemonic)

A helpful mnemonic to remember the common clinical features of Potter syndrome is: POTTER Mnemonic P: pulmonary hypoplasia O: oligohydramnios T: twisted skin (wrinkly skin) T: twisted face (Potter facies: low set ears, retrognathia, hypertelorism) E: extremity deformities (limb deformitie...
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Infantile hemangioma

Infantile hemangiomas are benign vascular neoplasms that are the most common head and neck tumors of infancy. They can occur virtually anywhere, but the majority are found in the head and neck regions. This article aims to be a generic discussion of the condition, for detailed and more specific...
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Hunka classification of pediatric septic arthritis of the hip

The Hunka classification is used to grade the residual anatomical deformity of the proximal femur following a septic hip in the pediatric population based on changes to the femoral head and stability of the hip. Classification type I: absent or minimal femoral head changes type II: IIa: defo...
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Kyphosis

Kyphosis (plural: kyphoses), much less commonly kyphus, is a term used to describe the sagittal curvature of the thoracic spine. Pathology Etiology An increased kyphotic angle is seen in the following conditions: Scheuermann disease spondyloarthropathies osteoporosis vertebral body fractu...
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Clear cell sarcoma of the kidney

Clear cell sarcomas of the kidney (CCSK) are a rare mesenchymal renal tumor that account for ~5% of primary renal neoplasms in the pediatric population 1.  Epidemiology Clear cell sarcoma of the kidney is the second most common primary malignant pediatric renal neoplasm after Wilms tumor, with...
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Salter-Thompson classification of Perthes disease

The Salter-Thompson classification of Perthes disease simplifies the Catterall classification into two groups. Based on the radiographic crescent sign, we can distinguish: group A: including Catteral groups I and II, where the crescent sign involves less than 50% of the femoral head group B: i...
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Endochondral ossification

Endochondral ossification describes the process of ossification from mesenchymal cells (stem cells) with a cartilaginous template and is involved in the healing process of fractures. Bone formation occurs at ossification centers, which are either primary or secondary: primary ossification cent...
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Intramembranous ossification

Intramembranous ossification describes the process of ossification from mesenchymal cells (stem cells) without a cartilaginous template and is involved in the healing process of fractures. The stages of intramembranous ossification osteogenesis are as follows: mesenchymal cells differentiate in...
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Lacuna magna

Lacuna magna, also known as the sinus of Guérin, is a congenital blind-ended pouch located dorsal to navicular fossa of penis separated by fold and both share an external common opening to external urethral meatus. This diverticulum is located above and parallel to the urethra.  Epidemiology A...
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Vitamin D

Vitamin D (calciferol) is used to describe a group of five fat-soluble secosteroid vitamins required for the homeostasis of serum calcium and phosphorus. Vitamin D exists in two main forms (vitamers) in humans: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3).  Vitamin D3 acts by re...
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Ossifying renal tumor of infancy

Ossifying renal tumor of infancy (ORTI) is a rare renal tumor. Epidemiology extremely rare, <<1% of pediatric renal neoplasms (17 cases reported) 6 days - 3 months male predominant Pathology Histology reveals spindle cells and osteoblastic cells in a calcified osteoid matrix. It is thought...
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Unifocalisation procedure

A unifocalisation procedure is a corrective surgical technique used in patients with complete pulmonary artery atresia with major aortopulmonary collateral arteries (MAPCAs). In this technique, the collateral vessels supplying blood from the aorta directly to the lungs are brought into continuit...
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Gage sign

The Gage sign is a V-shaped lucent defect at the lateral portion of the epiphysis and/or adjacent metaphysis. It is pathognomonic for Legg-Calve-Perthes disease. It may occur early in the disease and is one of the five indicators of a worse prognosis, which are: Gage sign calcification latera...
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Total repair of tetralogy of Fallot

Total repair of tetralogy of Fallot is a corrective surgical procedure that involves closure of the ventricular septal defect (VSD) and relief of right ventricular outflow tract (RVOT) obstruction. Procedure Most patients with tetralogy of Fallot (TOF) undergo elective surgical repair between ...
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Raghib syndrome

Raghib syndrome is a rare developmental complex. It consists of: persistence of the left superior vena cava coronary sinus ostial atresia atrial septal defect It has also been associated with other congenital malformations including ventricular septal defects, enlargement of the tricuspid an...
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Ductus venosus

Ductus venosus (DV) is a narrow, trumpet-shaped vessel which is seen in the fetal liver connecting the umbilical vein directly to the caudal inferior vena cava or distal left hepatic vein. The vessel plays a critical role in the fetal circulation by shunting oxygenated and nutrient-rich umbilica...
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Niemann-Pick disease type B

Niemann-Pick disease type B (NPD-B), along with Niemann-Pick disease type A (NPD-A), is an autosomal recessive disorder due to acid sphingomyelinase deficiency resulting in abnormal storage of sphingomyelin. Common manifestation of NPD-B includes hepatosplenomegaly, thrombocytopenia, and variab...
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Cystic leukoencephalopathy without megalencephaly

Cystic leukoencephalopathy without megalencephaly, is an autosomal-recessive inherited condition that manifests in the early childhood with moderate to severe psychomotor retardation and spasticity. On imaging, it is characterized by bilateral anterior subcortical temporal lobe cysts and extens...
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Catterall classification of Perthes disease

The Catterall classification of Perthes disease is based on radiographic appearances of the epiphysis and metaphysis visible in osteonecrosis of the femoral head: stage I bone absorption changes visible in the anterior aspect of the epiphysis of femoral head changes are visible best in frog l...
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Forearm fracture

Forearm fractures are a group of fractures that occur in the forearm following trauma. The radius and ulna are bound together at the proximal and distal radioulnar joints and act as a ring. Like elsewhere in the body, it is difficult to only fracture one bone if there is a bony ring. If the radi...
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Baumann angle

Baumann angle, also known as the humeral-capitellar angle, is used for the evaluation of the displacement of  pediatric supracondylar humeral fractures. It is measured on a frontal radiograph, with elbow in extension. This angle is formed  by the humeral axis and a straight line through the epi...
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Norrie disease

Norrie disease is a rare X-linked inherited cause of congenital bilateral blindness. It can present with a retinal mass (pseudoglioma) and cataracts. It is associated with developmental delay and hearing loss. 
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Blepharophimosis

Blepharophimosis is dysplasia of the eyelids, where there is horizontal shortening of palpebral fissure. It is often associated with ptosis. Blepharophimosis is a feature of Dubowitz syndrome and Smith Lemli Opitz syndrome. Blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) is c...
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Boot-shaped heart

A 'boot-shaped' heart ("cœur en sabot" in French) is the description given to the appearance of the heart on plain film in some cases of Tetralogy of Fallot. It describes the appearances of an upturned cardiac apex due to right ventricular hypertrophy and a concave pulmonary arterial segment. 
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Hemihyperplasia

Hemihyperplasia, also known as hemihypertrophy, is asymmetry in size between the right and left of the body, more than can be attributed to normal variation. Terminology Hemihyperplasia is more scientifically correct than hemihypertrophy as the cells are hyperplastic rather than hypertrophied ...
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Tibiotalar slant

Tibiotalar slant is the superolateral inclination of the tibial plafond, and results in an ankle valgus deformity. There are a number of causes 1: trauma, i.e. distal tibial fractures osteomyelitis and/or septic arthritis juvenile idiopathic arthritis haemophilic arthropathy sickle cell dis...
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Delta resistive index

The delta resistive index (delta RI or Δ RI) is a measurement that can be made when performing Doppler ultrasound. In preterm babies who have hydrocephalus secondary to intraventricular hemorrhage, the delta RI can be used to determine whether decompression of the ventricular system with an...
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Umbilical artery

The umbilical artery gives rise to both a nonfunctional remnant of the fetal circulation and an active vessel giving supply to the bladder. In the adult, the obliterated area of the vessel is identifiable as the medial umbilical ligament and the patent segment is the superior vesical artery. Su...
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Medulloepithelioma of the ciliary body

Medulloepitheliomas of the ciliary body are rare primary intraocular embryonal tumors arising from the ciliary body of the eye. Terminology Medulloepithelioma of the ciliary body is also referred to as diktyoma or teratoneuroma of the ciliary body. It is included among the "tumors of the iris ...
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Dravet syndrome

Dravet syndrome, previously known as severe myoclonic epilepsy of infancy (SMEI), is a rare form of epilepsy usually presenting in the first 1-2 years of life. Clinical presentation The typical presentation occurs during the first six months to one year of life as tonic-clonic seizures (includ...
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Pseudosubluxation of the cervical spine

Pseudosubluxation of the cervical spine is the physiological anterior displacement of C2 on C3 in children. It is common in children <7 years, and less often present in older children. Less often it is seen at C3 on C4. It is more pronounced in flexion and is of clinical significance as it can b...
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Urethral duplication

Urethral duplication is a rare condition in which either a part of the entire urethra is duplicated. It usually occurs in the sagittal plane and the more dorsal copy is usually the duplication. Pathology Urethral duplications may occur due to a variety of developmental anomalies. In females, i...
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Juvenile osteoporosis

Juvenile osteoporosis refers to osteoporosis occurring in children. Pathology Etiology It can arise from a number of causes 1-4: primary conditions osteogenesis imperfecta Bruck syndrome osteoporosis pseudoglioma syndrome Ehlers-Danlos syndrome Marfan syndrome homocystinuria secondary...
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Wiskott-Aldrich syndrome

Wiskott-Aldrich syndrome (WAS) is a rare immunodeficiency disease. Epidemiology The incidence currently quoted is approximately 4 per million live male births, although there can be regional variation. Rarely occurs in females. Associations splenic hamartoma infantile cortical hyperostosis ...
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Perthes disease (summary)

This is a basic article for medical students and other non-radiologists Perthes disease is the name given to idiopathic osteonecrosis of the femoral epiphysis in children. It most often occurs in children around the age of 5-6 years and is one of the common considerations when children present ...
Article

Fukuyama congenital muscular dystrophy

Fukuyama congenital muscular dystrophy (FCMD) is a form of congenital muscular dystrophy. Epidemiology FCMD is almost exclusively found in Japan where it has an incidence of 2-4 per 100,000 infants and is the second most common muscular dystrophy after Duchenne muscular dystrophy 1,2. However,...
Article

Thymic sail sign

The thymic sail sign represents a triangular-shaped inferior margin of the normal thymus seen on a neonatal frontal chest radiograph. It is more commonly seen on the right side, but can also be bilateral. It is seen in 3-15% of all cases. This sign should not be confused with the spinnaker sail ...
Article

Congenital pseudoarthrosis of the clavicle

Congenital pseudoarthrosis of the clavicle is a rare condition, which typically presents as an isolated anatomical variant.  Clinical presentation Usually presents as a midclavicular swelling in the neonate or young child 1.  Pathology Congenital pseudoarthrosis of the clavicle is more commo...
Article

Thymic notch sign

The thymic notch sign represents the normal thymus in a newborn on a frontal chest radiograph. Interruption of the cardiac silhouette forms a notch, which may be seen on either side, but more frequently is seen on the left side.   See also thymic sail sign thymic wave sign  
Article

Chronic hip subluxation

Chronic hip subluxation most common occurs in pediatric patients with neuromuscular disorders (e.g. cerebral palsy). It is considered a form of developmental hip dysplasia.  Epidemiology Chronic hip subluxation occurs in ~45% of cerebral palsy patients who are not walking by 5 years of age 3. ...
Article

Torticollis

Torticollis, also known as wry neck, is a clinical finding of head tilt with or without rotational spinal malalignment. It is not a diagnosis in itself and there are a wide range of underlying conditions. It is most common in the pediatric age group.  Pathology Torticollis can be acute (<1 wee...
Article

Pulmonary plethora

Pulmonary plethora is a term used to describe the appearances of increased pulmonary perfusion on chest radiographs. It is commonly used in pediatric radiology.  Pathology Usually a left-to-right shunt of 2:1 is required for pulmonary plethora to occur 2,3. Increased pulmonary perfusion occurs...
Article

Ossification centers of the foot

Primary ossification centers present at birth Visible on x-ray from birth: calcaneus: 6 months in utero talus: 7 months in utero cuboid: 9 months in utero metatarsals: 9 weeks in utero phalanges: 3-10 months (proximal to distal) Primary ossification centers developing after birth Become ...
Article

Cobb's collar

Cobb's collar (also known as a Moormann's ring or congenital narrowing of the bulbar urethra) is a membranous stricture of the bulbar urethra just downstream of the external urethral sphincter. It is sometimes referred to as a type III posterior urethral valve, and does not maintain a connection...
Article

Non-decussating retinal-fugal fiber syndrome

Non-decussating retinal-fugal fiber syndrome (NRFFS), also referred to as achiasma, is the isolated congenital absence of optic chiasm with unremarkable rest of the optic pathway and midline structures. Clinically, it typically presents as seesaw nystagmus since childhood. Diagnosis is usually m...
Article

Tamm-Horsfall proteins

Tamm-Horsfall proteins, also known as uromodulin, may be a cause of echogenic renal pyramids in a neonate. Tamm-Horsfall proteins are physiologically excreted by the renal tubular epithelium. They are most often encountered on neonatal renal ultrasound, where the concentrated proteins in the re...
Article

Takeuchi procedure

The Takeuchi procedure refers to a direct anastomosis of the anomalous left coronary artery from the pulmonary artery directly to the aorta was described in the 1970s and currently remains the procedure of choice. An intrapulmonary aortocoronary tunnel or baffle was performed by Takeuchi prior ...
Article

Hematuria (pediatric)

Hematuria in a child is evaluated differently than in an adult in two main respects: there is a lower likelihood of a malignancy (renal or bladder) causing the hematuria preference is given to nonionizing radiation Pathology Hematuria can be considered in three main forms: "gross" hematuria...
Article

Absent septum pellucidum

An absent septum pellucidum may rarely be an isolated finding, or more commonly be seen in association with a variety of conditions. Epidemiology The septum pellucidum is partly or entirely absent in 2 or 3 individuals per 100,000 in the general population.  Pathology An absent septum pelluc...
Article

Sincipital encephalocele

Sincipital encephaloceles are congenital herniations of cerebral parenchyma through a cranial defect. There are three main types 1,2: frontonasal encephalocele (~50%): more common in Asia and Latin America 4 nasoethmoidal encephalocele (30%): more common in North America 4 nasoorbital (nasola...

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