Articles
Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.
65 results found
Article
Hypovascular retroperitoneal lesions
Hypovascular retroperitoneal lesions are those which do not enhance in the late arterial and portal venous phases on CT. Some of these lesions may show progressive enhancement in the delayed phase due to their fibrous or myxoid matrix components.
Non-enhancing lesions
retroperitoneal lipoma
r...
Article
Hypervascular retroperitoneal lesions
Hypervascular retroperitoneal lesions are findings that enhance avidly in the late arterial phase with or without washout in the portal venous and delayed phases, on contrast-enhanced CT or MRI.
Early enhancement with slow washout
sympathetic paragangliomas
retroperitoneal paragangliomas - of...
Article
Penile calcification
Penile calcifications are a relatively rare finding. The commonest cause is Peyronie disease.
Pathology
Etiology
Peyronie disease
penile calciphylaxis (considered by some to be a form of calcinosis cutis)
penile urethral calculus
calcinosis cutis of the penis
idiopathic calcinosis cutis o...
Article
Renal emphysema
Renal emphysema, or intrarenal gas, refers to the presence of gas within the kidney, with or without extension to the urinary tract.
It is a rare finding and only a few differentials need to be considered 1:
infections
emphysematous pyelonephritis 1
iatrogenic
instrumentation
biopsy
surge...
Article
Ureteral calcification
Ureteral calcification refers to the presence of calcium concretions within the ureteral lumen or wall.
Common
ureteric calculi
Uncommon
neoplastic 3
transitional cell carcinoma
hemangioma
papilloma
infections
tuberculosis 1
schistosomiasis of the urinary tract
iatrogenic
radiation u...
Article
Abnormal testicular Doppler flow (differential)
Abnormal testicular Doppler flow (arterial, venous, or both) can be a differential challenge. Always remember that the patient's presenting history helps quite a bit in narrowing the differential.
Reduced flow
partial testicular torsion (<360 degrees)
venous outflow is obstructed first, resul...
Article
Pseudobladder
Pseudobladder refers to a pelvic cystic mass that simulates the urinary bladder.
The location of the lesion should allow differentiation from the bladder but if doubt exists and clinical necessity arises, a delayed phase CT/MRI with excreted contrast or Foley catheter-administered retrograde co...
Article
Pseudohydronephrosis
Pseudohydronephrosis (plural: pseudohydronephroses) refers to normal anatomy or non-significant pathologies that may mimic hydronephrosis. There is usually fluid-density material within a dilated part of the urinary tract, but without other signs of obstruction such as retroperitoneal fat strand...
Article
Solitary filling defect of the ureter (differential)
Solitary filling defect within a ureter, as seen on conventional IVU or CT IVU has some differentials, including:
within the lumen
calculus
sloughed papilla
blood clot
benign polyp
within the wall
transitional cell carcinoma (TCC)
tuberculosis
metastasis
endometriosis
When multiple ...
Article
Renal cortical defect
Renal cortical defects have a variety of causes, and present on imaging as an area of focal cortical thinning or absence of renal cortex, sometimes accompanied by focal caliectasis.
Differential diagnosis
The differential diagnosis for a renal cortical defect includes 1,2:
renal scarring
re...
Article
Congenital anomalies of the male urethra
Congenital anomalies of the male urethra include various anomalies due to complex development of urethra. These anomalies can be isolated or in association with other coexisting anomalies. They can be categorized as following:
urethral agenesis (or atresia)
congenital valves
posterior urethr...
Article
Valsalva maneuver
The Valsalva maneuver is the forced expiration of air against a closed airway, resulting in increased intra-abdominal, intrathoracic, and pharyngeal pressure. It can be performed against a closed glottis or by one closing the mouth and pinching the nose while forcibly exhaling.
It is commonly u...
Article
Prostatomegaly
Prostatomegaly is a term used to generally describe enlargement of the prostate gland from whatever cause. Usually, the prostate is considered enlarged on imaging when its volume measures beyond 30 cc (mL).
Terminology
The term prostatomegaly is often used interchangeably with benign prostati...
Article
Extratesticular scrotal mass (differential)
Extratesticular scrotal masses (not arising from testis or epididymis) are mostly mesenchymal in origin and benign 1.
Benign lesions
lipoma (most common)
leiomyoma of the scrotum
neurofibroma
granular cell tumor
angiomyofibroblastoma-like tumor
fibrous pseudotumor
fibrous hamartoma of i...
Article
Empyema
Empyemas are purulent inflammatory collections within a body cavity. Contrast this with abscesses, which arise within parenchymal tissue, rather than occupying a pre-existing anatomical space.
Terminology
Colloquially, the standalone term empyema is used to refer to thoracic empyemas but there...
Article
Fat containing renal lesions
There are numerous fat-containing renal lesions, including:
renal angiomyolipoma
renal cell carcinoma (often has calcifications when contains macroscopic fat)
Wilms tumor
renal oncocytoma
renal or perirenal lipoma/liposarcoma
Non-mass lesions may also occasionally contain fat:
renal junct...
Article
Cystic lesions around vagina and female urethra
There several cystic lesions around the vagina and female urethra; some of the imaging differential considerations would include:
urethral diverticulum
Gartner duct cyst: at or above the level of the pubic symphysis anterior to the vaginal wall
Bartholin gland cyst: posterolateral to distal v...
Article
HIV/AIDS (genitourinary manifestations)
Genitourinary manifestations of HIV/AIDS are protean and can be divided into:
HIV-associated nephropathy
renal diseases related to opportunistic infections: CMV, tuberculosis and MAC infections, fungal infections, pneumocystis carinii infection
drug-related renal diseases:
indinavir-induced ...
Article
Urinary diversion
Urinary diversion is created after the removal of the urinary bladder (radical cystectomy or cystoprostatectomy, usually done to treat invasive bladder cancer).
There are three main varieties:
neobladder formed from a segment of ileum (i.e. ileal conduit, also known as a "Bricker conduit")
th...
Article
Perinephric fluid collection post renal transplant
Perinephric fluid collections post renal transplant are common. The appearance of a perinephric fluid collection after renal transplantation is often non-specific but may be partially differentiated by how long ago the transplant occurred.
Radiographic features
Early post-transplant period (<4...
Article
Bladder wall thickening (differential)
Differential diagnosis for bladder wall thickening depends on whether the bladder is adequately distended. The bladder wall may be thickened if:
>3 mm when distended
>5 mm when nondistended
If the bladder is not distended, then it is difficult to exclude artifactual thickening from a collapse...
Article
Increased renal echogenicity
Increased renal echogenicity is a non-specific finding but can represent a number of underlying conditions.
These include:
normal variation
renal amyloidosis
chronic kidney disease: increased cortical echogenicity
sickle cell disease 4
See also
echogenic renal pyramids - pediatric
renal ...
Article
Right iliac fossa mass (differential)
Right iliac fossa mass is a common clinical presentation and has a range of differentials that need to be excluded. Radiology plays an important role in this differentiation.
Differential diagnosis
appendicular mass
appendicular abscess
appendicular mucocele
appendicular neoplasms
ileoceca...
Article
Urinary bladder diverticulum
A urinary bladder diverticulum (plural: diverticula) is an outpouching from the bladder wall, whereby mucosa herniates through the bladder wall. It may be solitary or multiple in nature and can vary considerably in size.
Epidemiology
There are two peaks; one at 10 years and the other at 60-70 ...
Article
Epididymal lesions
Epididymal lesions are most commonly encountered on ultrasonography. Most epididymal lesions are benign; malignant lesions are rare.
They can comprise of
Benign solid lesions
adenomatoid tumor of the scrotum: most common epididymal mass 4
epididymal leiomyoma
papillary cystadenoma of the e...
Article
Hydronephrosis
Hydronephrosis (plural: hydronephroses) is defined as dilatation of the urinary collecting system of the kidney (the calyces, the infundibula, and the pelvis) 1.
Hydronephrosis in fetuses and newborns has specific causes that are covered in a separate article.
Terminology
The term hydroureter...
Article
Renal vein varices
Renal vein varices (singular: varix) develop for various reasons and are usually asymptomatic.
Clinical presentation
Renal vein varices are usually asymptomatic. Some patients may present with flank pain and/or hematuria.
Pathology
Etiology
chronic renal vein thrombosis
nutcracker syndrom...
Article
Bilateral renal enlargement
Bilateral renal enlargement can arise from a number of causes which include 1,2:
Smooth enlargement
diabetic nephropathy (common)
acute pyelonephritis
renal involvement with lymphoma
acute interstitial nephritis
acute glomerulonephritis
acute urate nephropathy
vasculitis/autoimmune
HIV ...
Article
Intra-abdominal calcification (neonatal)
Intra-abdominal calcification in a neonate can be caused by a number of pathologies that cause calcification within the peritoneal space or within organs.
Pathology
Etiology
Meconium peritonitis
The commonest cause is meconium peritonitis which is the result of aseptic peritonitis secondary ...
Article
Medical devices in the abdomen and pelvis
Medical devices in the abdomen and pelvis are important to be recognized, just like medical devices of the chest. We often ignore these devices, considering them to be incidental and non-pathological, however it is essential to be aware of potential complications.
Gastrointestinal devices
tube...
Article
Congenital renal anomalies
Congenital renal anomalies comprise of vast spectrum of pathologies and include:
renal agenesis
renal dysgenesis
congenital renal hypoplasia
congenital megacalyectasis
congenital cystic renal disease
infantile polycystic renal disease: autosomal recessive polycystic kidney disease (ARPKD):...
Article
Low signal intensity renal parenchyma
There are relatively few causes of low signal intensity renal parenchyma. Causes include:
hemolysis
paroxysmal nocturnal hemoglobinuria
mechanical: malfunctioning prosthetic cardiac valve
sickle cell disease
infection
hemorrhagic fever with renal syndrome (HFRS)
vascular disease
acute re...
Article
Cystic retroperitoneal lesions
Cystic retroperitoneal lesions can carry a relatively broad differential, which includes:
retroperitoneal lymphatic malformation
retroperitoneal mucinous cystadenoma
retroperitoneal cystic teratoma
retroperitoenal cystic mesothelioma
pseudomyxoma retroperitonei with cystic change
perianal ...
Article
Obstructive uropathy
An obstructive uropathy is a catch-all term encompassing any cause of complete or partial, congenital or acquired, and permanent or intermittent obstruction of the urinary tract. Depending on the severity of obstruction and extent, it may result in permanent change in both the collecting system ...
Article
Tumors of the male urethra
Tumors of the male urethra are uncommon. They can be categorized both on the grounds of histology and location.
Histology
squamous cell carcinoma of the urethra: 80%
urothelial/transitional cell carcinoma of the urethra: 15% (predominantly posterior urethra)
adenocarcinoma of the urethra: 5%...
Article
Scrotal infections
The scrotum and its content are subject to a number of infective processes including:
scrotal cellulitis
scrotal abscess
Fournier gangrene
epididymitis
epididymo-orchitis
orchitis
testicular abscess
scrotal filariasis
Article
Urinary bladder wall or lumen calcification (differential)
Causes of urinary bladder wall or lumen calcification include:
Common
bladder calculus
schistosomiasis of the urinary tract
tuberculosis
Uncommon
neuroblastoma; pheochromocytoma
radiation reaction
alkaptonuria (ochronosis)
amyloidosis
calculus in a urachal cyst or in a bladder divertic...
Article
Bilateral adrenal gland enlargement
The differential for bilaterally enlarged adrenal glands (adrenomegaly) is relatively limited:
adrenal hyperplasia
micronodular adrenal hyperplasia
macronodular adrenal hyperplasia
adrenocorticotropin (ACTH)-independent macronodular adrenocortical hyperplasia (AIMAH) 2
adrenal metastases
a...
Article
Risk factors for testicular germ cell tumors
Risk factors for testicular germ cell tumors (GCT) include:
Caucasians at higher risk than African Americans (9:1)
undescended testis
10-40x increased risk
around 10% of all tumors are associated with undescended testis
higher risk if intra-abdominal testis compared with intrainguinal
orc...
Article
Cortical nephrocalcinosis
Renal cortical nephrocalcinosis is ~20 times less common than medullary nephrocalcinosis.
Pathology
Etiology
renal cortical necrosis: common 2
renal infarction/ischemia
sepsis
toxemia of pregnancy
drugs
snake bites
arsenic poisoning
extracorporeal shock wave lithotripsy (ESWL)
hemolyt...
Article
Medullary nephrocalcinosis
Renal medullary nephrocalcinosis is the commonest form of nephrocalcinosis and refers to the deposition of calcium salts in the medulla of the kidney. Due to the concentrating effects of the loops of Henle, and the biochemical milieu of the medulla, compared to the cortex, it is 20 times more co...
Article
Echogenic renal pyramids (differential)
Echogenic renal pyramids in children can be due to many different causes.
Differential diagnosis
Nephrocalcinosis
Iatrogenic (most common cause)
furosemide (frusemide)
vitamin D
steroids
Non-iatrogenic
idiopathic hypercalcemia
Williams syndrome
hyperparathyroidism
milk-alkali syndrom...
Article
Urinary bladder diverticula (causes)
There are numerous causes of urinary bladder diverticula:
Primary (congenital or idiopathic)
Hutch diverticulum (in paraureteral region)
Secondary
bladder outlet obstruction
bladder neck stenosis
neurogenic bladder
posterior urethral valve
prostatic enlargement (hypertrophy; carcinoma)
...
Article
Pyelonephritis
Pyelonephritis (plural: pyelonephritides) refers to an upper urinary (renal) tract infection with associated renal pelvis, renal calyceal and renal parenchymal inflammation, and comprises a heterogeneous group of conditions.
bacterial pyelonephritis
chronic pyelonephritis
renal tuberculosis
...
Article
Renal pseudotumor
A renal pseudotumor is a mass that will simulate a tumor on imaging but is composed of non-neoplastic tissue. There are many examples 1:
Developmental
prominent column of Bertin
persistent fetal lobulation
dromedary hump
splenorenal fusion
cross-fused renal ectopia
renal hilar lip
Infect...
Article
Paratesticular tumors
A paratesticular mass may derive from a number of structures that surround the testis within the scrotum; most commonly, they derive from the spermatic cord.
Pathology
The masses can be categorized as benign (70%) or malignant (30%).
Etiology
Benign
spermatic cord lipoma (most common parat...
Article
Prostate cystic disease
Prostate cystic disease encompasses a wide variety of pathologies that all result in cyst formation within the prostate.
Epidemiology
Prostatic cysts are common, and ~5-8% men will develop one 4,7. However they are much more common in patients being investigated for infertility, with one study...
Article
Chronic primary adrenal insufficiency
Chronic primary adrenal insufficiency has a number of causes. Primary adrenal insufficiency is termed Addison disease.
Pathology
Causes
idiopathic atrophy: autoimmune adrenalitis 1
tuberculosis 1: 25% calcify
fungal disease 1
histioplasmosis
blastomycosis
coccidioidomycosis
AIDS 1
sarc...
Article
Testicular cancer
Testicular cancers are the most common malignancy in men between the ages of 20 and 34 years.
Epidemiology
Testicular cancer is uncommon, accounting for less than 1% of all internal organ malignancies 2.
The commonest histology of the tumor varies with the age of affected individuals. Over 90...
Article
Testicular cystic lesions
Testicular cystic lesions are a relatively common occurrence on testicular ultrasound. They result from widely variable pathological entities ranging from benign to malignant. These entities include:
simple testicular cyst
tunica albuginea cyst (mesothelial cyst)
cystic transformation of rete...
Article
HIV associated neoplasms
HIV-associated neoplasms are numerous and can be broadly divided into two groups:
AIDS-defining malignancies
associated but not AIDS defining malignancies
AIDS-defining malignancies
The development of these malignancies in HIV affected individuals generally implies progression to AIDS 4:
Ka...
Article
Multiple filling defects of the ureter (differential)
Multiple filling defects within a ureter, as seen on conventional IVU or CT IVU, have a relatively small differential including:
spreading or multifocal transitional cell carcinoma (TCC)
vascular indentations
multiple ureteral stones (steinstrasse)
blood clots
ureteritis cystica
Stevens-Jo...
Article
Paratesticular lesions
Paratesticular lesions have a long list of differential diagnoses:
neoplastic
benign
epididymal cyst (most common epididymal mass)
scrotal tunica cysts
tunica vaginalis cyst
tunica albuginea cyst
spermatic cord lipoma
scrotal hemangioma: is often hypervascular on color Doppler, unlike ot...
Article
Epididymal calcification
Epididymal calcification can be seen on ultrasound as hyperechoic foci within the epididymal head. If the calcifications are large enough, then they may demonstrate acoustic shadowing.
Differential diagnosis
chronic epididymitis, e.g. bacterial, granulomatous (TB) or genital filariasis
traum...
Article
Prostate peripheral zone T2 hypointensity
Prostate peripheral zone T2 hypointensity is a common finding in pelvic MRIs that needs to be evaluated. A prostate MRI is usually performed with a multiparametric technique (mpMRI) to differentiate prostate cancer from more benign pathologies. mpMRI includes T2 weighted images, dynamic contrast...
Article
Adrenal calcification
Adrenal calcification is not a rare finding in healthy asymptomatic people and is usually the result of previous hemorrhage or tuberculosis. Addison disease patients only occasionally develop calcification.
Pathology
Etiology
Hemorrhage
sepsis: Waterhouse-Friderichsen syndrome
blunt abdomi...
Article
Extratesticular cystic lesions (differential)
The differential diagnosis for extratesticular cystic lesions includes:
hydrocele
epididymal cyst
spermatocele
hematoma
hematocele
loop of bowel from an inguinal hernia
abscess
pyocele
post-vasectomy
varicocele
Very rarely, a scrotal mesothelioma may present as a cystic mass.
Article
Bilateral testicular lesions
Bilateral testicular lesions have a relatively limited differential diagnosis.
Differential diagnosis
Neoplastic
lymphoblastic leukemia (acute or chronic)
lymphoma (non-Hodgkin's)
primary testicular lymphoma is rare but the testes are often the site of lymphoma/leukemia recurrence due to ...
Article
Unilateral testicular lesions
The differential diagnosis for unilateral testicular lesions is wide-ranging.
Neoplastic
Common
seminoma (40-50% of testicular malignancies)
non-seminomatous germ cell tumors:
testicular teratoma
testicular epidermoid (teratoma with ectodermal elements only)
testicular choriocarcinoma
t...
Article
Hyperreninaemic hypertension (differential)
Hyperreninaemic hypertension may have many causes including:
renal artery stenosis
renal secreting tumor, e.g. renal cell carcinoma, reninoma
renal compression: large renal mass, subcapsular hemorrhage (Page kidney)
Article
Renal artery stenosis
Renal artery stenosis (RAS) (plural: stenoses) refers to a narrowing of a renal artery. When the process occurs slowly, it leads to secondary hypertension. Acute renal artery stenosis does not lead to hypersecretion of renin.
Pathology
When the stenosis occurs slowly, collateral vessels form a...
Article
Pear-shaped bladder
Pear-shaped (or teardrop-shaped) bladder is one whose normal round or ovoid shape has been extrinsically compressed to resemble a pear. The pear may be inverted or upright, depending on how the excess pelvic tissue compresses the bladder.
Pathology
Etiology
Causes of a pear-shaped bladder inc...
Article
Pediatric renal tumors and masses
Pediatric renal tumors and masses are another group of diseases (just like cystic renal diseases in both the adult and child) that are bewildering in their number, nomenclature and overlapping findings.
Commoner lesions
Wilms tumor: common in older children 1-8 years old
nephroblastomatosis: ...
Article
Nephrocalcinosis
Nephrocalcinosis, previously known as Anderson-Carr kidney or Albright calcinosis, refers to the deposition of calcium salts in the parenchyma of the kidney. It is divided into several types, with differing etiologies, based on the distribution:
medullary nephrocalcinosis: 95%
cortical nephroc...
Article
Gas in the urinary bladder
There are numerous causes of gas in the urinary bladder. In the hospital setting by far the most common is the recent placement of an indwelling urinary catheter. Other causes include 1:
iatrogenic
indwelling urinary catheter is by far the most common cause
cystoscopy, etc.
emphysematous cys...