Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

22 results found
Article

Effect of insulin on FDG-PET

Insulin administration has an effect on FDG-PET by affecting the biodistribution of the radiotracer, F-18-fluorodeoxyglucose (FDG), the FDG organic ligand being an analog of glucose, posing a challenge for imaging those with diabetes mellitus. FDG-PET-CT is a hybrid imaging modality commonly us...
Article

CT chest abdomen-pelvis (protocol)

The CT chest-abdomen-pelvis protocol serves as an outline for an examination of the trunk covering the chest,  abdomen and pelvis. It is one of the most common CT examinations conducted in routine and emergencies. It can be combined with a CT angiogram. Note: This article aims to frame a genera...
Article

CT abdomen-pelvis (protocol)

The CT abdomen-pelvis protocol serves as an outline for an examination of the whole abdomen including the pelvis. It is one of the most common CT protocols for any clinical questions related to the abdomen and/or in routine and emergencies. It forms also an integral part of trauma and oncologic ...
Article

CT pancreas (protocol)

The CT pancreas protocol serves as an outline for a dedicated examination of the pancreas. As a separate examination, it is usually conducted as a biphasic contrast study and might be conducted as a part of other scans such as  CT abdomen-pelvis, CT chest-abdomen-pelvis. Note: This article aims...
Article

CT pelvis (protocol)

The CT pelvis protocol serves as an outline for the acquisition of a pelvic CT. As a separate examination, it might be performed as a non-contrast or contrast study or might be combined with a CT hip or rarely with a CT cystogram. A pelvic CT might be also conducted as a part of other scans such...
Article

Samarium-153

Samarium-153 (Sm-153) is a radioisotope used in metabolic radiotherapy for the treatment of pain from bone metastases. It is produced in nuclear reactors, by neutron irradiation of samarium-152 (Sm-152 Sm2O3). Samarium-153 decays by emitting both beta minus particles and gamma photons with a ch...
Article

Lymphoscintigraphy

Lymphoscintigraphy is a nuclear medicine technique to visualize regional lymphatic drainage, especially for mapping sentinel lymph nodes, from a site of radiopharmaceutical injection. Radiopharmaceutical Colloidal agents are used as these particles enter lymphatic channels and migrate to lymph...
Article

Choline C-11

Carbon-11-choline (choline C-11 or 11C-choline) is the most studied isotope carbon-11 PET radiopharmaceutical.  The molecule is used for oncologic Imaging 1-4. Choline is one of the components of phosphatidylcholine, a fundamental element of cell membrane phospholipids 5. Cancer cells tend to ha...
Article

F-18 fluorodeoxyglucose

F-18 fluorodeoxyglucose (FDG) is the most common PET radiotracer. Structure The radiopharmaceutical consists of the fluorine-18 radionuclide substituting the hydroxyl group at the C-2 position of glucose. The IUPAC chemical name is 2-deoxy-2-[F-18]fluoroglucose. Production F-18 fluoride ion ...
Article

Prostate MRI protocol

Prostate MRI has become an increasingly frequent examination faced in daily radiological practice and is usually acquired as either multiparametric or biparametric MRI of the prostate. This article aims to outline the concept of an MRI protocol for the assessment of the prostate. Recommendatio...
Article

Pion therapy

Pion therapy is a form of particle therapy employing pions. Pions, or to give them their full name, negatively-charged pi mesons (π-), are a type of meson. Pion therapy is currently not used as a treatment modality due to its great expense and lack of clinical efficacy 1,2.
Article

Neutron therapy

Neutron therapy is a form of particle therapy using neutrons as the energy-carrying particle. The therapy has shown promise for some malignancies but there have also been problems with accurate dose distributions and late complications. Some of these problems historically were thought to be - at...
Article

Particle therapy

Particle therapy (also known as hadronic therapy) is the generic term used for any type of external beam radiotherapy (EBRT) employing high-energy particles. Currently proton therapy accounts for most of this type of EBRT. Although strictly a form of particle therapy, electron therapy is usually...
Article

Magnetic resonance lymphangiography

Magnetic resonance lymphangiography (MRL) is an imaging technique used to visualize and map the lymphatic vessels. The technique is used for treatment planning in supermicrosurgical procedures, including lymphaticovenous anastomosis, lymphaticolymphatic bypass and vascularized lymph node transfe...
Article

Indocyanine green lymphangiography

Indocyanine green (ICG) lymphangiography is an emerging imaging technique used to visualize lymphatic vessels and map their course as they drain to sentinel lymph nodes.  History Indocyanine green is a fluorescent dye discovered by researchers at Kodak working on near-infrared photography in 1...
Article

Gallium-68 DOTATATE

Gallium-68 DOTATATE​​ (or Ga-68 DOTATATE) is a PET radiotracer that is useful for evaluating primary and metastatic well-differentiated neuroendocrine tumors. It is a form of somatostatin-receptor (SSTR) functional imaging and most often combined with cross-sectional imaging in the form of PET-C...
Article

Computed tomography texture analysis

Computed tomography texture analysis (or CTTA) is a method to obtain new useful biomarkers that provide objective and quantitative assessment of tumor heterogeneity by analyzing the differences and patterns within the pixel values of an image. CTs can be worked with as a matrix of numbers, corre...
Article

Radiation-induced carcinogenesis

Radiation-induced carcinogenesis is widely but not universally believed to occur at exposures from ionizing radiation used in medical imaging. It is thought to be a stochastic effect of ionizing radiation, with the linear no-threshold theory (LNT) proposing no "safe" level of radiation exposure,...
Article

Radiation-induced lung cancer

Radiation-induced lung cancers are a potential long-term complication of radiotherapy to the chest.  Besides lung cancer, sarcomas (osteosarcomas are the most common arising from the irradiated bones, and malignant fibrous histiocytomas the most frequently arising from the soft tissues), breast...
Article

Positron emission tomography

Positron emission tomography (PET) is a modern non-invasive imaging technique for quantification of radioactivity in vivo. It involves the intravenous injection of a positron-emitting radiopharmaceutical, waiting to allow for systemic distribution, and then scanning for detection and quantificat...
Article

Myo-inositol peak

Myo-inositol is one of the compounds images with MR spectroscopy (MRS) at both 1.5 T and 3 T and is seen to resonate at 3.5 ppm chemical shift (right of the choline peak).  Myo-inositol is a precursor of both phosphatidylinositol (the major inositol-containing phospholipid) and phosphatidylinos...
Article

Thorotrast

Thorotrast is a suspension of radioactive thorium dioxide first produced in Germany in 1928, used as a contrast agent until the 1950s. Its principal use was for cerebral angiography: 90% of the estimated 50,000-100,000 patients treated received it for this purpose. Umbrathor was another thorium ...

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