Segmental pancreatitis is not a distinct entity in itself but describes an imaging differential.
With segmental pancreatitis, a patient presents with clinical pancreatitis (signs, symptoms, laboratory markers), but on imaging, only a portion of the gland appears to have changes related to pancreatitis.
It is not uncommon for part of the pancreas to be disproportionally affected in acute pancreatitis, but with segmental pancreatitis, parts of the gland are normal-appearing on imaging.
The imaging differential varies depending on whether the involved segment is the head of the pancreas or the tail.
Head of pancreas
Tail of pancreas
The most important thing to assess is whether a mass in the pancreas (such as pancreatic adenocarcinoma) is obstructing the duct and causing obstructive pancreatitis in the upstream gland. Similarly, a stone obstructing the pancreatic duct could cause upstream pancreatitis in the tail. Once these are excluded, other possibilities can be considered, such as
- 1. Shanbhogue AK, Fasih N, Surabhi VR, Doherty GP, Shanbhogue DK, Sethi SK. A clinical and radiologic review of uncommon types and causes of pancreatitis. Radiographics : a review publication of the Radiological Society of North America, Inc. 29 (4): 1003-26. doi:10.1148/rg.294085748 - Pubmed
- 2. Sahani DV, Kalva SP, Farrell J, Maher MM, Saini S, Mueller PR, Lauwers GY, Fernandez CD, Warshaw AL, Simeone JF. Autoimmune pancreatitis: imaging features. Radiology. 233 (2): 345-52. doi:10.1148/radiol.2332031436 - Pubmed
- cystic neoplasm (cystic pancreatic mass differential diagnosis)
- solid neoplasm
- nonepithelial pancreatic neoplasms
- simple pancreatic cyst
pancreatitis (mnemonic for the causes)
- gallstone pancreatitis
- interstitial oedematous pancreatitis
- necrotising pancreatitis
- haemorrhagic pancreatitis
- revised Atlanta classification of acute pancreatitis
- chronic pancreatitis
- Ascaris-induced pancreatitis
- tropical pancreatitis
- autoimmune pancreatitis
- emphysematous pancreatitis
- hereditary pancreatitis
- pancreatitis associated with cystic fibrosis
- segmental pancreatitis
- acute pancreatitis
- pancreatic atrophy
- pancreatic lipomatosis
- pancreatic trauma