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Sex cord / stromal testicular tumors

Last revised by Arlene Campos on 5 Jul 2023

Sex cord / stromal testicular tumors are uncommon testicular neoplasms. Although ~90% of these tumors are benign, they cannot be differentiated from testicular malignancies on imaging, and are therefore usually discovered after orchiectomy.

Epidemiology

They are uncommon testicular neoplasms with a mildly increased incidence in pediatric patients.

  • 4% of all testicular neoplasms in the general population

  • 11% of all testicular neoplasms in those <12 years old

Pathology

These tumors arise from cells that form the sex cords (Sertoli cells) and those that form the testicular stroma (Leydig cells).

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