Sex cord stromal tumors of the testis

Last revised by Dr Jeremy Jones on 20 Sep 2021

Sex cord stromal tumors of the testis are uncommon testicular neoplasms. Although ~90% of these tumors are benign, they cannot be differentiated from testicular malignancies on imaging, and are therefore usually discovered after orchiectomy.

Epidemiology

Uncommon testicular neoplasms with mildly increased incidence in pediatric patients

  • 4% of all testicular neoplasms
  • 11%, if <12 years old.

Pathology

These tumors arise from cells that form the sex cords (Sertoli cells) and those that form the testicular stroma (Leydig cells).

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