Sickle cell disease (cerebral manifestations)

Cerebral manifestations of sickle cell disease (SCD) contribute significantly to the overall morbidity of the disease. SCD is among the most common causes of stroke in the paediatric population.

For a general discussion of sickle cell disease, please refer to sickle cell disease.

Approximately 25% of patients with sickle cell disease have a neurological event in their lifetime, many of these in childhood 1

Ischaemic strokes and cognitive impairment are common, but in many instances, infarcts may be asymptomatic 1-2

Cerebral radiological findings in SCD include 1-3:

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Article information

rID: 12459
System: Head & Neck
Synonyms or Alternate Spellings:
  • Cerebral manifestations of sickle cell anemia
  • Cerebral manifestations of sickle cell anaemia
  • Cerebral manifestations of sickle cell disease

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