Sickle cell disease (skeletal manifestations)

Skeletal manifestations of sickle cell disease result from a combination of bone marrow hyperplasia in the setting of chronic anaemia, and bone infarction as well as their complications.

For a general discussion of sickle cell disease, please refer to sickle cell disease.

Bone pain is a frequent complaint, although vaso-occlusive events may also be silent.

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Article information

rID: 12457
Section: Pathology
Synonyms or Alternate Spellings:
  • Skeletal manifestations of sickle cell anaemia
  • Skeletal manifestations of sickle cell anemia

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Cases and figures

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    Sickle cell disea...
    Case 1: with H-shaped vertebrae
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    Case 3: with AVN of the hip
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    Case 4: with bone infarct
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    Case 5: with avascular necrosis of the hip
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    Case 6: with osteomyelitis
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    Case 7: with H-shaped vertebrae
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