Silent sinus syndrome
The silent sinus syndrome represents maxillary sinus atelectasis that results in painless enophthalmos, hypoglobus and facial asymmetry 1-3. Some authors restrict the term to patients with no history of sinusitis, trauma or surgery 2.
Silent sinus syndrome usually presents in the third to fifth decade, without a gender predilection. In general, the condition is idiopathic. However, in a small number of patients, trauma to the lateral nasal wall and ostiomeatal complex may be the cause, e.g. endonasal intubation 1-2.
Presentation is typically with painless and usually relatively long-standing (months to years) facial asymmetry, enophthalmos of 2-5 mm, and hypoglobus 1-3. Symptoms of sinusitis are not always present 1. Where there is significant deformity of the orbital floor, patients may develop diplopia. However, extraocular movements are usually normal 2.
Chronic occlusion of the maxillary sinus ostium/ostia results in gradual resorption of the air. Subsequently, negative pressure is generated within the sinus 3. This in turn results in gradual inward bowing of all four of the maxillary walls: roof (orbial floor), medial, posterolateral and anterior walls. Orbital volume increases with resultant enophthalmos and variable flattening of the malar eminence 1.
A number of other hypotheses have been advanced, including inflammatory erosion and softening of walls due to chronic sinusitis; or sinusitis in a hypoplastic sinus 4. However, manometric measurement in a number of cases have confirmed the presence of negative pressures, as well as proof of normal sized sinuses on previous imaging 3 - these make the latter two hypotheses unlikely.
Although the diagnosis is usually made clinically, usually by otolaryngologists and ophthalmologists, imaging of the sinuses confirms the findings. Additionally, the diagnosis may be made incidentally on imaging of the region for other reasons.
Plain radiographs are no longer considered sufficiently sensitive or specific for the assessment of paranasal sinus disease. However, they are still not infrequently performed. The findings are the same as those seen on CT (see below).
CT, preferably performed as a volumetric acquisition with three-plane orthogonal reformats, is able to elegantly demonstrate changes in the sinus and the adjacent structures.
The sinus is fully formed, but fully opacified and reduced in volume with inward bowing of all four walls. This manifests as 1:
- inferior bowing of the roof (orbital floor): increased orbital volume and enophthalmos
- lateral bowing of the medial wall: lateral displacement of the middle and inferior turbinate
- posterior bowing of the anterior wall: flattening of the malar eminence
- anteromedial bowing of the posterolateral wall
MRI is not required for the diagnosis. If it is performed, it will demonstrate (in addition to the anatomical changes above) a fully opacified sinus with thickening and enhancement of the mucosa. The secretions are of variable intensity.
Treatment and prognosis
The condition is benign but may result in diplopia. Treatment involves the creation of a drainage route for the sinus. This can be with a nasal antral window or maxillary antrostomy.
Once drainage is established, no further volume loss will develop. However, any deformity at the time of surgery will be permanent and may require surgical correction, especially if diplopia is present.
The differential is usually small. However, conditions to be considered include:
- 1. Illner A, Davidson HC, Harnsberger HR et-al. The silent sinus syndrome: clinical and radiographic findings. AJR Am J Roentgenol. 2002;178 (2): 503-6. AJR Am J Roentgenol (full text) [pubmed citation]
- 2. Hobbs CG, Saunders MW, Potts MJ. "Imploding antrum" or silent sinus syndrome following naso-tracheal intubation. Br J Ophthalmol. 2004;88 (7): 974-5. doi:10.1136/bjo.2003.035386 [free text at pubmed] [pubmed citation]
- 3. Davidson JK, Soparkar CN, Williams JB et-al. Negative sinus pressure and normal predisease imaging in silent sinus syndrome. Arch. Ophthalmol. 1999;117 (12): 1653-4. doi:10.1001/archopht.117.12.1653 [pubmed citation]
- 4. Eto RT, House JM. Enophthalmos, a sequela of maxillary sinusitis. AJNR Am J Neuroradiol. 1995;16 (4): 939-41. AJNR Am J Neuroradiol (abstract) [pubmed citation]
- 5. Kilty SJ. Maxillary sinus atelectasis (silent sinus syndrome): treatment with balloon sinuplasty. J Laryngol Otol. 2014;128 (02): 189-91. doi:10.1017/S0022215113003538 - Pubmed citation
- inflammatory and infective conditions
- granulomatosis with polyangiitis (Wegener granulomatosis)
- paranasal sinus mucocoele
- silent sinus syndrome
- masses and neoplasms
- fibrous-osseous lesions