Small cell carcinoma (urinary bladder)
Citation, DOI & article data
- Small cell carcinoma of the bladder
- Small cell carcinomas of the bladder
- Poorly differentiated neuroendocrine carcinoma of the bladder
Small cell carcinomas of the bladder are rare bladder cancers with a poor prognosis. Its appearance overlaps other bladder cancers, in particular, urothelial/transitional cell carcinoma.
On this page:
Epidemiology
A very rare tumor, it has been estimated at <0.0001% of bladder cancers. It is thought to have a predominance in caucasian patients and those with a smoking history.
Clinical presentation
Hematuria and pain are the most common symptoms. Its presentation overlaps that of other bladder tumors, such as urothelial/transitional cell carcinoma; there is no specific presentation.
Radiographic features
The appearance is similar to urothelial/transitional cell carcinoma: an enhancing polypoid bladder mass. There are no imaging finding specific to the tumor.
Treatment and prognosis
Prognosis is poor, with <10% five year survival for disease confined to the pelvis 4.
Differential diagnosis
- urothelial/transitional cell carcinoma (much more common)
References
- 1. Wong-You-Cheong JJ, Woodward PJ, Manning MA et-al. From the Archives of the AFIP: neoplasms of the urinary bladder: radiologic-pathologic correlation. Radiographics. 2006;26 (2): 553-80. doi:10.1148/rg.262055172 - Pubmed citation
- 2. Kim JC, Kim KH, Jung S. Small cell carcinoma of the urinary bladder: CT and MR imaging findings. Korean J Radiol. 2003;4 (2): 130-5. Free text at pubmed - Pubmed citation
- 3. Abrahams NA, Moran C, Reyes AO et-al. Small cell carcinoma of the bladder: a contemporary clinicopathological study of 51 cases. Histopathology. 2005;46 (1): 57-63. doi:10.1111/j.1365-2559.2004.01980.x - Pubmed citation
- 4. Lohrisch C, Murray N, Pickles T et-al. Small cell carcinoma of the bladder: long term outcome with integrated chemoradiation. Cancer. 2000;86 (11): 2346-52. Pubmed citation
Related articles: Pathology: Genitourinary
- obstetrics
-
first trimester
- ultrasound findings in early pregnancy
- embryo/fetus
- beta-hCG levels
- confirming intrauterine gestation
- pregnancy of unknown location (PUL)
- first trimester vaginal bleeding
- early structural scan
- aneuploidy testing
-
second trimester
- fetal biometry
- amniotic fluid volume
- fetal morphology assessment
- soft markers
- amnioreduction
- Doppler ultrasound
- nuchal translucency
- 11-13 weeks antenatal scan
- chorionic villus sampling (CVS) and amniocentesis
- other
- placenta
- placental anatomy
- placental developmental abnormalities
- placenta previa
- spectrum of abnormal placental villous adherence
- abnormalities of cord insertion
- abruptio placentae
- placental pathology
- vascular pathologies of placenta
- placental infections
- placental masses
- molar pregnancy
- twin placenta
- miscellaneous
-
first trimester
- gynecology
- acute pelvic pain
- chronic pelvic pain
- uterus
- ovaries
- ovarian follicle
- ovarian torsion
- pelvic inflammatory disease
- ovarian cysts and masses
- paraovarian cyst
- polycystic ovaries
- ovarian hyperstimulation syndrome
- post-hysterectomy ovary
- cervix
- fallopian tube
- other
- male genital tract
- prostate gland
- transrectal ultrasound
- prostate tumors
- infections of the prostate
-
prostatitis
- acute bacterial prostatitis
-
chronic prostatitis
- chronic bacterial prostatitis
- chronic prostatitis and chronic pelvic pain syndrome (CPPS)
- asymptomatic inflammatory prostatitis
- granulomatous prostatitis
- emphysematous prostatitis
- prostatic abscess
-
prostatitis
- benign prostatic hypertrophy
- cystic lesions of the prostate
- prostatic calcification
- prostatic infarction
- testes
-
unilateral testicular lesion
- testicular torsion
- orchitis
- testicular rupture
-
germ cell tumors of the testis
- testicular seminoma
-
non seminomatous germ cell tumors
- mixed germ cell tumor
- yolk sac tumor (endodermal sinus tumor)
- embryonal cell carcinoma
- choriocarcinoma
- testicular teratoma
- testicular epidermoid (teratoma with ectodermal elements only)
- burned out testis tumor
- sex cord / stromal tumors of the testis
- testicular cyst
- testicular lymphoma
- bilateral testicular lesion
- paratesticular lesions
- epididymis
- other
- polyorchidism
- cryptorchidism
- tubular ectasia of the rete testis
- cystadenoma of the rete testis
- testicular sarcoidosis
- testicular tuberculosis
- spermatic cord
- fibrous pseudotumor of the scrotum
- scrotal leiomyosarcoma
- testicular adrenal rest tumors (TARTs)
- tunica vaginalis testis mesothelioma
- splenogonadal fusion
- testicular vasculitis
- abnormal testicular Doppler flow (differential)
-
unilateral testicular lesion
- penis
- prostate gland
- KUB
- kidneys
- normal renal anatomy
- hydronephrosis
- urolithiasis
- renal masses
- renal cystic disease
- renal infection
- vascular
- trauma
- ureter
- normal ureter anatomy
- ureteral stricture
- ureteral dilatation
- ureteral anomalies
- ureteral tumors
- ureteral trauma
- other
- bladder
- kidneys