Small cell carcinoma (urinary bladder)
Citation, DOI & article data
Small cell carcinomas of the bladder are rare bladder cancers with a poor prognosis. Its appearance overlaps other bladder cancers, in particular, urothelial/transitional cell carcinoma.
A very rare tumor, it has been estimated at <0.0001% of bladder cancers. It is thought to have a predominance in caucasian patients and those with a smoking history.
Hematuria and pain are the most common symptoms. Its presentation overlaps that of other bladder tumors, such as urothelial/transitional cell carcinoma; there is no specific presentation.
The appearance is similar to urothelial/transitional cell carcinoma: an enhancing polypoid bladder mass. There are no imaging finding specific to the tumor.
Treatment and prognosis
Prognosis is poor, with <10% five year survival for disease confined to the pelvis 4.
- urothelial/transitional cell carcinoma (much more common)
- 1. Wong-You-Cheong JJ, Woodward PJ, Manning MA et-al. From the Archives of the AFIP: neoplasms of the urinary bladder: radiologic-pathologic correlation. Radiographics. 2006;26 (2): 553-80. doi:10.1148/rg.262055172 - Pubmed citation
- 2. Kim JC, Kim KH, Jung S. Small cell carcinoma of the urinary bladder: CT and MR imaging findings. Korean J Radiol. 2003;4 (2): 130-5. Free text at pubmed - Pubmed citation
- 3. Abrahams NA, Moran C, Reyes AO et-al. Small cell carcinoma of the bladder: a contemporary clinicopathological study of 51 cases. Histopathology. 2005;46 (1): 57-63. doi:10.1111/j.1365-2559.2004.01980.x - Pubmed citation
- 4. Lohrisch C, Murray N, Pickles T et-al. Small cell carcinoma of the bladder: long term outcome with integrated chemoradiation. Cancer. 2000;86 (11): 2346-52. Pubmed citation