Soap bubble appearance (differential diagnosis)

Last revised by Joachim Feger on 25 Jan 2023

Soap bubble appearance describes a multi-loculated bubbly appearance of lesion or structure.

A soap bubble appearance of a bone lesion refers to:

  • an expansile lytic lesion with internal trabeculations and preserved cortex, usually of benign nature 

  • but may be used to describe more aggressive lesions

The differential includes:

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