Citation, DOI, disclosures and article data
Citation:
Abdeldjalil B, Gaillard F, Soap bubble appearance (DNET). Reference article, Radiopaedia.org (Accessed on 29 Mar 2024) https://doi.org/10.53347/rID-163587
Disclosures:
At the time the article was last revised Frank Gaillard had the following disclosures:
- Biogen Australia Pty Ltd, Investigator-Initiated Research Grant for CAD software in multiple sclerosis: finished Oct 2021 (past)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Frank Gaillard's current disclosures
The soap bubble appearance, also known as the bubbly appearance, has been described in dysembryoplastic neuroepithelial tumors (DNET). It describes a multi-loculated pseudocystic appearance of the DNET on T2 weighted images 1,2. These areas show partial suppression on FLAIR and are often associated with a bright rim of high signal (bright rim sign).
This bubbly appearance should not be mistaken for the salt-and-pepper appearance of polymorphous low-grade neuroepithelial tumor of the young (PLNTY), due to small distributed calcifications throughout the tumor 2.
Nor should it be confused for the much larger areas of flair suppression seen in some diffuse astrocytomas, the so-called T2/FLAIR mismatch sign.
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1. Paudel K, Borofsky S, Jones R, Levy L. Dysembryoplastic Neuroepithelial Tumor with Atypical Presentation: MRI and Diffusion Tensor Characteristics. J Radiol Case Rep. 2013;7(11):7-14. doi:10.3941/jrcr.v7i11.1559 - Pubmed
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2. Chen Y, Tian T, Guo X et al. Polymorphous Low-Grade Neuroepithelial Tumor of the Young: Case Report and Review Focus on the Radiological Features and Genetic Alterations. BMC Neurol. 2020;20(1):123. doi:10.1186/s12883-020-01679-3 - Pubmed
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