Citation, DOI, disclosures and article data
Citation:
Gaillard F, Knipe H, Weerakkody Y, et al. Solitary sclerotic bone lesion. Reference article, Radiopaedia.org (Accessed on 24 Apr 2024) https://doi.org/10.53347/rID-8429
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Radiopaedia Events Pty Ltd, Speaker fees (past)
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Henry Knipe's current disclosures
Solitary sclerotic bone (osteosclerotic or osteoblastic) lesions are lesions of bone characterised by a higher density or attenuation on radiographs or computer tomography compared to the adjacent trabecular bone. However, a specific density range has not been specified for those terms 1.
The differential diagnosis of solitary sclerotic bone lesions can be narrowed down according to the following factors 1-3:
Concerning the above factors the differential diagnosis includes the following lesions 1-3:
ADVERTISEMENT: Supporters see fewer/no ads
aggressive features → might require an oncological referral and/or biopsy 1
history of malignancy → will almost always require additional imaging, follow-up or oncologic referral
high CT attenuation values might help in the differentiation of bone island from osteoblastic metastases 5 but attenuation values should not be used exclusively for the assessment of sclerotic bone lesions 6
-
1. Chang C, Garner H, Ahlawat S et al. Society of Skeletal Radiology- White Paper. Guidelines for the Diagnostic Management of Incidental Solitary Bone Lesions on CT and MRI in Adults: Bone Reporting and Data System (Bone-RADS). Skeletal Radiol. 2022;51(9):1743-64. doi:10.1007/s00256-022-04022-8 - Pubmed
-
2. Gulati V, Chalian M, Yi J, Thakur U, Chhabra A. Sclerotic Bone Lesions Caused by Non-Infectious and Non-Neoplastic Diseases: A Review of the Imaging and Clinicopathologic Findings. Skeletal Radiol. 2021;50(5):847-69. doi:10.1007/s00256-020-03644-0 - Pubmed
-
3. Adam Greenspan, Gernot Jundt, Wolfgang Remagen. Differential Diagnosis in Orthopaedic Oncology. (2007) ISBN: 9780781779302 - Google Books
-
4. Hall F & Gore S. Osteosclerotic Myeloma Variants. Skeletal Radiol. 1988;17(2):101-5. doi:10.1007/BF00365135 - Pubmed
-
5. Ulano A, Bredella M, Burke P et al. Distinguishing Untreated Osteoblastic Metastases From Enostoses Using CT Attenuation Measurements. AJR Am J Roentgenol. 2016;207(2):362-8. doi:10.2214/AJR.15.15559 - Pubmed
-
6. Azar A, Garner H, Rhodes N, Yarlagadda B, Wessell D. CT Attenuation Values Do Not Reliably Distinguish Benign Sclerotic Lesions From Osteoblastic Metastases in Patients Undergoing Bone Biopsy. AJR Am J Roentgenol. 2021;216(4):1022-30. doi:10.2214/AJR.20.24029 - Pubmed
-
7. Park S, Lee I, Cho K et al. Systematic Approach of Sclerotic Bone Lesions Basis on Imaging Findings. J Korean Soc Radiol. 2014;71(1):39. doi:10.3348/jksr.2014.71.1.39
Promoted articles (advertising)