Spermatic cord liposarcoma
Citation, DOI, disclosures and article data
At the time the article was created Michael P Hartung had no recorded disclosures.View Michael P Hartung's current disclosures
At the time the article was last revised Henry Knipe had the following disclosures:
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to not be relevant to the changes that were made.View Henry Knipe's current disclosures
Spermatic cord liposarcomas are the most common malignant tumor of the spermatic cord. Most present as painless, slow-growing masses and can be mistaken for inguinal hernias. They are usually well-differentiated and spread by local extension.
In a large population-based registry, the annual incidence of spermatic cord tumor (SCT) is 0.3 cases/million 3.
Most are low-grade and well-differentiated and spread by local extension. High-grade tumors can spread via hematogenous or lymphatic routes 3.
In a large population-based registry, 362 patients with SCT were identified, with histological subtypes of liposarcoma (46%), leiomyosarcoma (20%), histiocytoma (13%), and rhabdomyosarcoma (9%) 3.
CT and MRI provide greater characterization and staging information than ultrasound. They appear as a fat-containing tumor with variable amounts of soft tissue, nodularity, and septations.
Treatment and prognosis
Standard surgical treatment includes high orchiectomy and resection of the tumor and spermatic cord. Lymph node dissection is occasionally performed. Chemotherapy and radiation therapy depend on the tumor grade, stage, and risk of recurrence1.
Lipoma is the most common benign tumor of the spermatic cord, and much more common than liposarcoma (45% of paratesticular masses)3. Other malignant tumors of the spermatic cord include leiomyosarcoma, histiocytoma, and rhabdomyosarcoma.
- 1. Yamamichi G, Nakata W, Yamamoto A, Tsujimura G, Tsujimoto Y, Nin M, Tsujihata M. Liposarcoma of the spermatic cord associated with scrotum lipoma: A case report and review of the literature. (2018) Urology case reports. 17: 114-116. doi:10.1016/j.eucr.2018.01.022 - Pubmed
- 2. Rodríguez D, Barrisford GW, Sanchez A et-al. Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes. Urol. Oncol. 2014;32 (1): 52.e19-25. doi:10.1016/j.urolonc.2013.08.009 - Pubmed citation
- 3. Akbar SA, Sayyed TA, Jafri SZ, Hasteh F, Neill JS. Multimodality imaging of paratesticular neoplasms and their rare mimics. (2003) Radiographics : a review publication of the Radiological Society of North America, Inc. 23 (6): 1461-76. doi:10.1148/rg.236025174 - Pubmed
- 4. Woodward PJ, Schwab CM, Sesterhenn IA. From the archives of the AFIP: extratesticular scrotal masses: radiologic-pathologic correlation. (2003) Radiographics : a review publication of the Radiological Society of North America, Inc. 23 (1): 215-40. doi:10.1148/rg.231025133 - Pubmed
- 5. Li F, Tian R, Yin C, Dai X, Wang H, Xu N, Guo K. Liposarcoma of the spermatic cord mimicking a left inguinal hernia: a case report and literature review. (2013) World journal of surgical oncology. 11: 18. doi:10.1186/1477-7819-11-18 - Pubmed
- 6. Chalouhy C, Ruck JM, Moukarzel M, Jourdi R, Dagher N, Philosophe B. Current management of liposarcoma of the spermatic cord: A case report and review of the literature. (2017) Molecular and clinical oncology. 6 (3): 438-440. doi:10.3892/mco.2017.1157 - Pubmed