Spindle cell carcinoma of lung
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Di Muzio B, Hacking C, et al. Spindle cell carcinoma of lung. Reference article, Radiopaedia.org (Accessed on 14 Jan 2025) https://doi.org/10.53347/rID-22593
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22593
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Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Bruno Di Muzio had no recorded disclosures.
View Bruno Di Muzio's current disclosures
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9 times, by
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Synonyms:
- Monophasic sarcomatoid carcinoma of lung
- Monophasic sarcomatoid carcinoma of lungs
- Pleomorphic (spindle) cell carcinoma of lungs
- Pulmonary spindle cell carcinomas
- Pulmonary spindle cell carcinoma
- Spindle cell carcinoma of lungs
- Spindle cell carcinomas of lungs
- Spindle cell carcinoma of the lung
- Spindle cell carcinoma of the lungs
Spindle cell carcinomas of the lung correspond to a very rare type of non-small cell lung carcinomas (NSCLC) classified under sarcomatoid carcinomas of the lungs.
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Terminology
Although, in the past, some authors also used the term synonymously with pleomorphic carcinoma of the lung, since the 1999 version of the WHO classification of tumors, spindle cell carcinomas of the lung are considered as a separate entity.
Pathology
Tumors usually show a concurrent presence of malignant epithelial and homologous sarcomatoid spindle cell components by co-expressing cytokeratin and vimentin in various degrees.
Radiographic features
We do not know of any specific imaging features specifically for this tumor. The lesion may either present as endobronchial lesions or peripheral parenchymal lesions.
References
- 1. Chang YL, Lee YC, Shih JY et-al. Pulmonary pleomorphic (spindle) cell carcinoma: peculiar clinicopathologic manifestations different from ordinary non-small cell carcinoma. Lung Cancer. 2001;34 (1): 91-7. Pubmed citation
- 2. Matsui K, Kitagawa M. Spindle cell carcinoma of the lung. A clinicopathologic study of three cases. Cancer. 1991;67 (9): 2361-7. Pubmed citation
- 3. Morimoto M, Osaki T, Kodate M, Nagaie T, Yamamoto H, Oya M. Spindle cell carcinoma of the lung. (2011) General thoracic and cardiovascular surgery. 59 (2): 129-32. doi:10.1007/s11748-010-0607-x - Pubmed
- 4. Chu KA, Lin SL, Wang HC, Lu JY, Su JM, Chiang HT. Spindle cell carcinoma of the lung: a clinicopathologic presentation of three cases. (1998) Zhonghua yi xue za zhi = Chinese medical journal; Free China ed. 61 (3): 164-9. Pubmed
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