Spindle cell carcinoma of lung
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At the time the article was created Yuranga Weerakkody had no recorded disclosures.View Yuranga Weerakkody's current disclosures
At the time the article was last revised Bruno Di Muzio had no recorded disclosures.View Bruno Di Muzio's current disclosures
Although, in the past, some authors also used the term synonymously with pleomorphic carcinoma of the lung, since the 1999 version of the WHO classification of tumors, spindle cell carcinomas of the lung are considered as a separate entity.
Tumors usually show a concurrent presence of malignant epithelial and homologous sarcomatoid spindle cell components by co-expressing cytokeratin and vimentin in various degrees.
We do not know of any specific imaging features specifically for this tumor. The lesion may either present as endobronchial lesions or peripheral parenchymal lesions.
- 1. Chang YL, Lee YC, Shih JY et-al. Pulmonary pleomorphic (spindle) cell carcinoma: peculiar clinicopathologic manifestations different from ordinary non-small cell carcinoma. Lung Cancer. 2001;34 (1): 91-7. Pubmed citation
- 2. Matsui K, Kitagawa M. Spindle cell carcinoma of the lung. A clinicopathologic study of three cases. Cancer. 1991;67 (9): 2361-7. Pubmed citation
- 3. Morimoto M, Osaki T, Kodate M, Nagaie T, Yamamoto H, Oya M. Spindle cell carcinoma of the lung. (2011) General thoracic and cardiovascular surgery. 59 (2): 129-32. doi:10.1007/s11748-010-0607-x - Pubmed
- 4. Chu KA, Lin SL, Wang HC, Lu JY, Su JM, Chiang HT. Spindle cell carcinoma of the lung: a clinicopathologic presentation of three cases. (1998) Zhonghua yi xue za zhi = Chinese medical journal; Free China ed. 61 (3): 164-9. Pubmed