Spindle cell rhabdomyosarcoma
Citation, DOI & article data
Spindle cell rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma.
There may be increased male predilection. May present at any age
Histologically this tumor can resemble a leiomyosarcoma. It is composed mainly of fascicular, relatively monomorphic spindle-shaped cells that show unequivocal immunohistochemical and ultrastructural evidence of myogenic differentiation.
There is predilection for the paratesticular region and the head and neck.
Treatment and prognosis
Compared to other rhabdomyosarcomas, it has a good prognosis 1.
- 1. Imaging of Soft Tissue Tumors. F. Vanhoenacker (Editor), A.M. De Schepper (Editor), P.M. Parizel (Editor), J. Gielen (Editor). Springer ISBN:3540248099 (find it at amazon.com)
- 2. Nascimento AF, Fletcher CD. Spindle cell rhabdomyosarcoma in adults. Am. J. Surg. Pathol. 2005;29 (8): 1106-13. Pubmed citation
- 3. Rubin BP, Hasserjian RP, Singer S et-al. Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis. Am. J. Surg. Pathol. 1998;22 (4): 459-64. Pubmed citation
- 4. Carroll SJ, Nodit L. Spindle cell rhabdomyosarcoma: a brief diagnostic review and differential diagnosis. Arch. Pathol. Lab. Med. 2013;137 (8): 1155-8. doi:10.5858/arpa.2012-0465-RS - Pubmed citation