Splenic epidermoid cyst

Splenic epidermoid cysts are a type of non-parasitic primary splenic cyst.

They are thought to account for 10-25% of benign non-parasitic cysts of the spleen 3. There may be an increased female predilection.

The clinical presentation can vary ranging from being incidentally discovered on routine imaging to having nausea, vomiting, vague abdominal pain or rarely painful splenomegaly.

They are congenital in origin. As “true” cysts, they have an epithelial lining formed secondary to infolding of peritoneal mesothelium or collections of peritoneal mesothelial cells trapped within the splenic sulci 9. A genetic defect of mesothelial migration is considered the cause. While most are sporadic, rarely there is a familial occurrence 6. They typically grow slowly and are usually large (around 10 cm) at the time of discovery. They are solitary in 80%. Peripheral calcifications are uncommon (10-15%).

Usually shows an anechoic to hypoechoic well defined intrasplenic lesion. Internal echoes may be present.

Typically shows a hypoattenuating relatively well defined intrasplenic lesion. The wall is thin and has a sharp demarcation to splenic parenchyma. There is no rim or internal enhancement. Wall calcification may be present.

Complications are rare and include haemorrhage, rupture and infection 4-5.

Small and asymptomatic cysts do not require treatment. Symptomatic cysts are managed surgically.

A number of splenic lesions may appear cystic, depending on the modality (for a complete list see cystic lesions of the spleen article). They include:

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Article information

rID: 24028
Tag: cases
Synonyms or Alternate Spellings:
  • Epidermoid cyst of the spleen
  • Splenic epidermoid cysts
  • Epidermoid cyst of spleen
  • Epidermoid cysts of spleen
  • Epidermoid cysts of the spleen

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