Splenic metastases

Last revised by Joshua Kogan on 14 May 2024

Splenic metastases are relatively rare on imaging and are more commonly encountered at autopsy. Typically they are part of a widespread metastatic disease.

The rate of splenic metastases varies between 1-10% of autopsy studies, depending on whether microscopic or macroscopic metastases were included 1.

Most commonly metastases are a solitary splenic (solid or cystic) mass, may rarely be infiltrative 1,4. Primary sources include 1,2,5:

  • solitary or multiple well-defined masses

  • most commonly appear as a hypoechoic lesion (target appearance), although can be iso- or hyperechoic 3,5

  • contrast-enhanced US (CEUS): rapid wash-in and wash-out 5

  • usually hypoattenuating masses

  • cystic components may be present 5

  • T1: low signal intensity

  • T2: high signal intensity

  • C+ (Gd): variable, mostly depending on the primary malignancy 5

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