Splenic peliosis is an unusual benign disorder characterized by the presence of irregular cystic blood-filled cavities.
Most patients are asymptomatic although very rarely, a patient can present with spontaneous rupture of the spleen.
Recognized associations include
- use of anabolic steroids
- hematological conditions such as aplastic anemia
- wasting diseases such as
May be seen as an echogenic mass lesion with numerous poorly defined foci of varying hypoechogenicity 5.
On non-contrast-enhanced CT images, typically seen as a hypo-attenuating, multi-loculated lesion with well-defined septae within.
On contrast-enhanced CT images, the lesion may show significant enhancement with loss of definition of the lobules and septae. Fluid–fluid levels may also be present.
History and etymology
The term originates from the Greek pelios (Πήλιος), meaning dusky or purple, which arose from the macroscopic appearance of the lesion.
- 1. Singh-Ranger G, Rajarajan N, Aftab S, Stoker D. Splenic peliosis - a potentially fatal condition which can mimick malignancy. (2007) International seminars in surgical oncology : ISSO. 4: 27. doi:10.1186/1477-7800-4-27 - Pubmed
- 2. Lashbrook DJ, James RW, Phillips AJ, Holbrook AG, Agombar AC. Splenic peliosis with spontaneous splenic rupture: report of two cases. (2006) BMC surgery. 6: 9. doi:10.1186/1471-2482-6-9 - Pubmed
- 3. Chieng GH, Zanetto U, Harper E. Splenic peliosis: an incidental finding. (2010) BMJ case reports. doi:10.1136/bcr.04.2010.2935 - Pubmed
- 4. Davidson J, Tung K. Splenic peliosis: an unusual entity. (2010) The British journal of radiology. 83 (990): e126-8. doi:10.1259/bjr/71300465 - Pubmed
- 5. Robert M. Abbott, Angela D. Levy, Nadine S. Aguilera, Luis Gorospe, William M. Thompson. From the Archives of the AFIP. (2004) RadioGraphics. 24 (4): 1137-63. doi:10.1148/rg.244045006 - Pubmed