Splenic peliosis

Splenic peliosis is an unusual benign disorder characterized by the presence of irregular cystic blood-filled cavities.

Most patients are asymptomatic although very rarely, a patient can present with spontaneous rupture of the spleen.

Recognized associations include

May be seen as an echogenic mass lesion with numerous poorly defined foci of varying hypoechogenicity 5

On non-contrast-enhanced CT images, typically seen as a hypo-attenuating, multi-loculated lesion with well-defined septae within.

On contrast-enhanced CT images, the lesion may show significant enhancement with loss of definition of the lobules and septae. Fluid–fluid levels may also be present.

The term originates from the Greek pelios (Πήλιος), meaning dusky or purple, which arose from the macroscopic appearance of the lesion.

Article information

rID: 68127
Synonyms or Alternate Spellings:
  • Peliosis of the spleen

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