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The squeeze sign is a pathognomonic feature of a colonic lipoma, where the lesion is seen to change in size and shape upon compression. This can be demonstrated with a barium enema examination where a well-circumscribed, spherical filling defect will be seen to elongate during peristalsis 1,2. The sign can also be elicited by direct compression during ultrasound scanning.
- 1. Gould D, Anne Morrison C, Liscum K, Silberfein E. A Lipoma of the Transverse Colon Causing Intermittent Obstruction: A Rare Cause for Surgical Intervention. Gastroenterol Hepatol (N Y). 2011;7(7):487-90. PMC3264899 - Pubmed
- 2. Tascilar O, Cakmak G, Gün B et al. Clinical Evaluation of Submucosal Colonic Lipomas: Decision Making. World J Gastroenterol. 2006;12(31):5075-7. doi:10.3748/wjg.v12.i31.5075 - Pubmed