Stauffer syndrome

Last revised by Daniel J Bell on 5 Jun 2019

Stauffer syndrome is paraneoplastic nephrogenic hepatomegaly. It most commonly occurs in the setting of renal cell carcinoma, and is the enlargement of the liver without hepatic metastases. It is a cause of cholestasis and cholestatic jaundice

History and etymology

It is named after Maurice H Stauffer, American gastroenterologist, working at the Mayo Clinic, who first described it in 1961.

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