Stevens Johnson syndrome

Dr Henry Knipe et al.

Stevens Johnson syndrome (SJS) is an acute inflammatory skin condition. 


SJS is on a spectrum of disease with toxic epidermal necrolysis (TEN) at the more severe end. Terminology depending on how much surface area is involved 1,2:

  • SJS: <10%
  • SJS-TEN overlap: 10-30%
  • TEN: >30%


SJS is very rare, with an incidence of 1-2 per 1,000,000 3


SJS is thought to be triggered by preceding viral infection or more commonly medication use (e.g. NSAIDs, antibiotics, anticonvulsants). Skin and mucosal surface (e.g. gastrointestinal, genital, conjunctival) with blistering and shedding is characteristic 1-3.

Share article

Article information

rID: 42135
Section: Syndromes
Tag: skin, cases
Synonyms or Alternate Spellings:
  • Stevens-Johnson syndrome (SJS)

Support Radiopaedia and see fewer ads

Updating… Please wait.

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.