Strawberry skull

Last revised by Daniel J Bell on 11 Feb 2018

Strawberry skull refers to the shape of the head on an antenatal ultrasound.



In general, strawberry skull is considered one of the non-specific 'soft markers' for abnormal fetal development. It is considered more closely associated with trisomy 18 (Edward syndrome).

Radiographic features

Antenatal ultrasound
  • brachycephaly with an increased cephalic index
  • flattened occiput (due to hypoplasia of occipital lobes, brainstem and cerebellum)
  • pointed frontal bones with hypoplasia of the frontal lobes of the brain

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