Strawberry skull

Last revised by Arlene Campos on 20 Aug 2024

Strawberry skull refers to the shape of the head on an antenatal ultrasound.

Epidemiology

Associations

In general, strawberry skull is considered one of the non-specific 'soft markers' for abnormal fetal development. It is considered more closely associated with trisomy 18 (Edward syndrome).

Radiographic features

Ultrasound
  • brachycephaly with an increased cephalic index

  • flattened occiput (due to hypoplasia of occipital lobes, brainstem and cerebellum)

  • pointed frontal bones with hypoplasia of the frontal lobes of the brain

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