A superscan is intense symmetric activity in the bones with diminished renal and soft tissue activity on a Tc-99m diphosphonate bone scan.
This appearance can result from a range of causes:
- diffuse metastatic disease
- metabolic bone diseases
- wide spread Paget disease
A metastatic superscan tends to have uptake throughout the axial skeleton and proximal appendicular skeleton, often somewhat heterogeneous. In contrast, a metabolic superscan tends to be more uniform and involve both the axial and more peripheral skeleton, including the distal extremities, calvarium, and mandible.
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