Synthetic MRI

Last revised by Adam Jasne on 6 Oct 2022

Citation, DOI, disclosures and article data

Citation:

Elgendy A, Jasne A, St-Amant M, Synthetic MRI. Reference article, Radiopaedia.org (Accessed on 23 Apr 2024) https://doi.org/10.53347/rID-57820

DOI:

https://doi.org/10.53347/rID-57820

Permalink:

https://radiopaedia.org/articles/57820

rID:

57820

Article created:

15 Jan 2018, Azza Elgendy

Disclosures:

At the time the article was created Azza Elgendy had no recorded disclosures.

View Azza Elgendy's current disclosures

Last revised:

6 Oct 2022, Adam Jasne

Disclosures:

At the time the article was last revised Adam Jasne had no financial relationships to ineligible companies to disclose.

View Adam Jasne's current disclosures

Revisions:

3 times, by 3 contributors - see full revision history and disclosures

Sections:

Imaging Technology

Synonyms:

Synthetic imaging

Synthetic MRI is a technique that generates contrast weighted images based on measurements of tissue properties from a single acquisition.

Basic principles

With synthetic MRI, different contrast weighted images can be obtained based on quantifications of a single multiple dynamic and multiple echo scan. The quantifications include the magnetic property of each tissue T1, T2 and proton density, using mainly the water molecules in the brain. A three-dimensional single acquisition scan is used to create a set of T1, T2, FLAIR, PD and STIR. The current technique is only applicable for creating structural MRI such as T1, T2, PD, FLAIR and STIR; the technique is not applicable for acquiring DWI.

The technique enables the reconstruction of multiple sequences from one single scan and thus reduces the scanning time. This property is especially useful in pediatrics, for uncooperative patients, and may also be interesting for patients with multiple follow-ups.

MAGnetic resonance image Compilation (MAGiC) software is an example of the available post processing softwares to obtain the synthetic images ^1,2.

Pitfalls

The previous literature suggested the inadequacy of using the synthetic FLAIR, compared to the conventional FLAIR, due to the increased the susceptibility artifacts in the synthetic FLAIR sequence. However, these artifacts are easily recognisable and do not mimic pathology ³.