Time-to-Maximum (Tmax)

Last revised by Frank Gaillard on 15 Sep 2020

Citation, DOI, disclosures and article data

Citation:

Gaillard F, Time-to-Maximum (Tmax). Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-82131

DOI:

https://doi.org/10.53347/rID-82131

Permalink:

https://radiopaedia.org/articles/82131

rID:

82131

Article created:

15 Sep 2020, Frank Gaillard ◉ ◈

Disclosures:

At the time the article was created Frank Gaillard had no recorded disclosures.

View Frank Gaillard's current disclosures

Last revised:

15 Sep 2020, Frank Gaillard ◉ ◈

Disclosures:

At the time the article was last revised Frank Gaillard had no recorded disclosures.

View Frank Gaillard's current disclosures

Revisions:

1 time, by 1 contributor - see full revision history and disclosures

Systems:

Central Nervous System

Synonyms:

T-max
Tmax

Time-to-Maximum (Tmax) is a perfusion parameter used both in CT perfusion and MRI perfusion and reflects the time delay between the contrast bolus arriving in the proximal large vessel arterial circulation (arterial input function) and the brain parenchyma ¹. It is calculated by deconvoluting the arterial input function ¹.

Although Tmax is widely used in defining tissue at risk of infarction in the setting of ischemic stroke it is susceptible to a variety of distortions particularly in the setting of inflow vascular abnormalities ^1,2.