T-shaped uterus
Citation, DOI, disclosures and article data
Citation:
Radswiki T, Niknejad M, Jones J, et al. T-shaped uterus. Reference article, Radiopaedia.org (Accessed on 03 Dec 2024) https://doi.org/10.53347/rID-13161
Permalink:
rID:
13161
Article created:
6 Mar 2011,
The Radswiki ◉
Disclosures:
At the time the article was created The Radswiki had no recorded disclosures.
View The Radswiki's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Mohammad Taghi Niknejad had no recorded disclosures.
View Mohammad Taghi Niknejad's current disclosures
Revisions:
7 times, by
6 contributors -
see full revision history and disclosures
Systems:
Synonyms:
- T-shaped configuration of the endometrial cavity
- T-shaped configuration to the endometrial cavity
- T-shaped configuration to endometrial cavity
- In utero diethylstilbestrol (DES) exposure
- In utero diethylstilbestrol exposure
- T shaped uterus
T-shaped uterus refers to a specific radiographic appearance of the endometrial cavity.
On this page:
Pathology
It is the most commonly associated abnormality from in utero diethylstilbestrol (DES) exposure, seen in 31% of exposed women. It is classified as a class VII Müllerian duct anomaly.
Background
DES is a synthetic estrogen that was introduced in 1948 and was prescribed for women experiencing recurrent spontaneous abortions, premature deliveries, and other pregnancy complications. By increasing the synthesis of placental steroidal hormones, DES was thought to decrease the frequency of pregnancy loss.
Radiographic features
Hysterosalpingogram (HSG)
Typically shows a narrowed irregular endocervical canal. The opacified endometrial cavity appears small, with a shortened upper uterine segment, resulting in the characteristic T-configuration.
Complications
In utero exposure to DES was shown to be associated with clear cell carcinoma of the vagina/cervix. The use of the drug was therefore abruptly discontinued in 1971 (incidence 0.14-1.4 per 1000 women exposed).
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Differential diagnosis
Considerations include:
- infantile: prepubertal uterus
- this appearance can also be observed in adult women with severe estrogen deficiencies in which the uterus fails to attain postpubertal proportions because of the absence of normal estrogen stimulus 2
- it may be seen in patients taking oral contraceptives for long periods of time 2
Quiz questions
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References
- 1 .Troiano RN, Mccarthy SM. Mullerian duct anomalies: imaging and clinical issues. Radiology. 2004;233 (1): 19-34. doi:10.1148/radiol.2331020777 - Pubmed citation
- 2. Ubeda B, Paraira M, Alert E et-al. Hysterosalpingography: spectrum of normal variants and nonpathologic findings. AJR Am J Roentgenol. 2001;177 (1): 131-5. AJR Am J Roentgenol (full text) - Pubmed citation
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