T2 shine-through refers to high signal on DWI images that is not due to restricted diffusion, but rather to high T2 signal which 'shines through' to the DWI image. T2 shine through occurs because of long T2 decay time in some normal tissue.
To confirm true restricted diffusion one should always compare the DWI image to the ADC. In cases of true restricted diffusion, the region of increased DWI signal will demonstrate low signal on ADC.
ADC is a value that measures the effect of diffusion independent of the influence of T2 shine-through. ADC maps thus portray restricted diffusion, such as in ischaemic injury, as hypointense lesions relative to normal brain.
In contrast, in cases of T2 shine-through, the ADC will be normal or high signal.
- 1. Luna A, Ribes R, Soto JA. Diffusion MRI Outside the Brain, A Case-Based Review and Clinical Applications. Springer Verlag. (2012) ISBN:3642210511. Read it at Google Books - Find it at Amazon
- 2. Burdette JH, Elster AD, Ricci PE. Acute cerebral infarction: quantification of spin-density and T2 shine-through phenomena on diffusion-weighted MR images. Radiology. 1999;212 (2): 333-9. Radiology (full text) - Pubmed citation
- 3. Koh D-, Amoozadeh Y(, Blackledge M( et-al. Diffusion-Weighted MR Imaging, Applications in the Body. Springer Verlag. (2010) ISBN:3540785752. Read it at Google Books - Find it at Amazon
- 4. Silvera S, Oppenheim C, Touzé E et-al. Spontaneous intracerebral hematoma on diffusion-weighted images: influence of T2-shine-through and T2-blackout effects. AJNR Am J Neuroradiol. 2005;26 (2): 236-41. AJNR Am J Neuroradiol (full text) - Pubmed citation
- 5. Casey S. "T2 washout": an explanation for normal diffusion-weighted images despite abnormal apparent diffusion coefficient maps. AJNR Am J Neuroradiol. 2001;22 (8): 1450-1. AJNR Am J Neuroradiol (full text) - Pubmed citation