Tachycardia induced cardiomyopathy

Tachycardia induced cardiomyopathy (TIC) (or tachycardiomyopathy) is considered a reversible form of acquired cardiomyopathy where there is impaired left ventricular systolic dysfunction precipitated by a tachycardia or a tachyarrhythmia.

Typically there is an impairment left ventricular systolic function measured by an impairment left ventricular ejection fraction (LVEF) precipitated in a context of a tachycardia or tachyarrhythmia. The LVEF would return to normal limits upon restoration of normal sinus rhythm. 

In adults, the most common etiologic arrhythmias are supraventricular in origin. It has occurred in all age groups, from neonates to adults, with patient risk based on the rhythm present; incessant atrial tachycardia (ectopic/focal) may induce TIC in up to 28% of patients. Commonly associated rhythms in adults causing TIC include 5:

  • atrial fibrillation
  • atrial flutter
  • atrial tachycardia
  • re-entrant supraventricular tachycardias (SVTs)
    • junctional reciprocating tachycardia
    • less commonly AVNRT/AVRT (usually paroxysmal)

Ectopic atrial tachycardias are the most common etiological factor in pediatric cases. Idiopathic ventricular tachycardia, as well as frequent ventricular ectopic beats, may rarely cause TIC.

Usually there is marked improvement in systolic function after normalization of heart rate. The disturbances in vascular resistance, cardiac output, and ventricular filling pressures are usually reversible over the course of weeks; ventricular volumes, however, may remain persistently elevated for longer periods of time. 

It is thought to have been first described by G H Whipple in 1967.

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Article information

rID: 37033
System: Cardiac
Synonyms or Alternate Spellings:
  • Tachycardiomyopathy
  • Systolic dysfunction associated with chronic tachyarrhythmias
  • Systolic dysfunction associated with chronic tachyarrhythmia
  • Tachycardia mediated cardiomyopathy
  • Tachycardia mediated cardiomyopathy (TMC)

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Cases and figures

  • Moderately severe...
    Case 1: tachycardia-induced cardiomyopathy
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  • Case 2: tachycardia mediated cardiomyopathy
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