Talcosis

A.Prof Frank Gaillard et al.

Talcosis is a type of pneumoconiosis and can be prevalent in intravenous drug users. It is one of the four recognised types talc induced lung disease.

Talc (magnesium silicate) is used in the preparation of tablets intended for oral use, where it acts as a 'filler' and lubricant. When these tablets are ground down, dissolved and injected the talc accumulates in the pulmonary circulation. These deposits result in small foreign body reaction granulomas, which are birefringent under polarized light. If use is persistent the nodules can coalesce to form larger masses.

Intrinsically hyperdense micronodules (<1mm) can be visible on CT.

CT
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Article information

rID: 6541
System: Chest
Tag: cases
Synonyms or Alternate Spellings:
  • Talcosis
  • Talcosis of lung
  • Talcosis of lungs
  • Talcosis of the lung
  • Pulmonary talcosis

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