Tamm-Horsfall proteins

Last revised by Yaïr Glick on 10 Sep 2019

Tamm-Horsfall proteins, also known as uromodulin, may be a cause of echogenic renal pyramids in a neonate.

Tamm-Horsfall proteins are physiologically excreted by the renal tubular epithelium. They are most often encountered on neonatal renal ultrasound, where the concentrated proteins in the renal pyramids may mimic nonobstructing renal stones 1. It is considered a normal finding 2.

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