Citation, DOI, disclosures and article data
Citation:
Di Muzio B, État lacunaire. Reference article, Radiopaedia.org (Accessed on 28 Mar 2025) https://doi.org/10.53347/rID-35368
État lacunaire is a term describing the presence of multiple lacunar infarcts, which are ischaemic strokes due to occlusion of penetrating cerebral arterioles, especially in the basal ganglia. The term has been strongly described as a pathological substrate for a multi-infarct vascular dementia 4.
It should be differentiated from état criblé, which is related to multiple enlarged perivascular spaces.
History and etymology
It was first described by Pierre Marie, a French neurologist, in 1901 1.
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1. Marie, Pierre. Des foyers lacunaires de désintégration et de différents autres états cavitaires du cerveau. Félix Alcan, 1901.
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2. Román GC. From UBOs to Binswanger's disease. Impact of magnetic resonance imaging on vascular dementia research. Stroke. 1996;27 (8): 1269-73. doi:10.1161/01.STR.27.8.1269 - Pubmed citation
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3. Barkhof F, Fox NC, Bastos-Leite AJ et-al. Neuroimaging in Dementia. Springer Science & Business Media. (2011) ISBN:3642008186. Read it at Google Books - Find it at Amazon
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4. Rabinstein A, Resnick SJ. Practical Neuroimaging in Stroke. Elsevier Health Sciences. (2009) ISBN:1455745952. Read it at Google Books - Find it at Amazon
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