Citation, DOI, disclosures and article data
At the time the article was created Yuranga Weerakkody had no recorded disclosures.View Yuranga Weerakkody's current disclosures
At the time the article was last revised Daniel J Bell had no recorded disclosures.View Daniel J Bell's current disclosures
Tc99m-Mebrofenin: trimethyl bromo IDA, also known as TBIDA, or under the trade name Choletec, is a diagnostic radiopharmaceutical used in hepatobiliary imaging. It is one of the Tc99m IDA (iminodiacetic acid) analogs. It is taken up by hepatocytes through the same membrane transport mechanism as bilirubin and then promptly secreted into the bile (without conjugation). It is considered a useful tool in the assessment of liver function reserve (especially in those considered for liver resections).
- 1. Olthof PB, Coelen RJS, Bennink RJ, Heger M, Lam MF, Besselink MG, Busch OR, van Lienden KP, van Gulik TM. Tc-mebrofenin hepatobiliary scintigraphy predicts liver failure following major liver resection for perihilar cholangiocarcinoma. (2017) HPB : the official journal of the International Hepato Pancreato Biliary Association. 19 (10): 850-858. doi:10.1016/j.hpb.2017.05.007 - Pubmed
- 2. Gupta M, Choudhury PS, Singh S, Hazarika D. Liver Functional Volumetry by Tc-99m Mebrofenin Hepatobiliary Scintigraphy before Major Liver Resection: A Game Changer. (2018) Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India. 33 (4): 277-283. doi:10.4103/ijnm.IJNM_72_18 - Pubmed
- 3. de Graaf W, van Lienden KP, van Gulik TM, Bennink RJ. (99m)Tc-mebrofenin hepatobiliary scintigraphy with SPECT for the assessment of hepatic function and liver functional volume before partial hepatectomy. (2010) Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 51 (2): 229-36. doi:10.2967/jnumed.109.069724 - Pubmed