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Testicular choriocarcinoma is a type of non-seminomatous germ cell tumor.
Incidence peaks at around 20-30 years of age.
Can be variable with some patients initially presenting with metastases.
It is most commonly detected as a component of a mixed malignant germ cell tumor and observed in about 7-8% of testicular tumors. It is extremely rare in pure form, choriocarcinoma comprising only 0.2-0.6% of all testis tumors.
b-HCG levels tend to be elevated.
Treatment and prognosis
It is considered an aggressive malignancy. Choriocarcinoma can often spread hematogenously. Treatment options include orchiectomy +/- combination chemotherapy.